Sort   by:  
 Page size 
TranscriptomicsMicroarray for B cells of TACI-IgG-treated MRL/lpr mice compared to control mice
Both multiple myeloma (MM) and systemic lupus erythematosus (SLE) are characterized with abnormal production of plasma cells. In both diseases, the process of B cells differentiate into plasmablast/plasma cell is disordered. Despite the continuous research on the development of prognostic factors an...
ORGANISM(S): Mus musculus 
2019-07-30 | E-MTAB-7106 | biostudies-arrayexpress
GenomicsEndogenous B cell TACI-Short-APRIL signaling
Endogenous B cell TACI-Short-APRIL signaling
PRJNA883412 | ENA
ProteomicsMulti-omics Analysis of naive B cells of patients harboring the C104R mutation in TACI
Common variable immunodeficiency (CVID) is the most prevalent form of symptomatic primary immunodeficiency in humans. The genetic cause of CVID is still unknown in about 70% of cases. 10% of CVID patients carry heterozygous mutations in the tumor necrosis factor receptor superfamily member 13B gene ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD035459 | Pride
Atac-seq Cd40l stimulation Dna accessibility Proteomics Taci Tnfrsf13b Transcription factor Cvid Naïve b cells Nf-b Rna-seq 
GenomicsTranscriptome analysis of TACI-deficient and WT naïve T cells
Transcriptome analysis of TACI-deficient and WT naïve T cells
PRJNA638270 | ENA
GenomicsTranscriptome of TACI KO and WT mouse marginal zone and follicular B cells
Transcriptome of TACI KO and WT mouse marginal zone and follicular B cells
PRJNA1279969 | ENA
TranscriptomicsEndogenous B cell TACI-Short-APRIL signaling
Here we show that TACI-S increases its expression with maturation and colocalizes in the intracellular compartment with the ligand APRIL. APRIL downregulation in human B cells, eliminated class switch. These studies suggest the importance of intracellular APRIL together with TACI-S in maintaining hu...
ORGANISM(S): Homo sapiens 
2023-09-22 | GSE213981 | GEO
TranscriptomicsTranscriptome of TACI KO and WT mouse marginal zone and follicular B cells
The mature peripheral B cell compartment consists of follicular (FO) and marginal zone (MZ) B cells, which mature from transitional B cells in the spleen and mount T-dependent and T-independent antibody responses, respectively. TACI (Tnfrsf13b) is a member of the TNF-receptor superfamily expressed o...
ORGANISM(S): Mus musculus 
2026-04-01 | GSE300247 | GEO
TranscriptomicsTranscriptome analysis of TACI-deficient and WT naïve T cells
TACI (transmembrane activator and calcium modulator and cyclophilin ligand interactor) plays critical roles in B cells by promoting immunoglobulin class-switching and plasma cell survival. However, its expression and function in T cells remain controversial. In this study, we found that TACI deficie...
ORGANISM(S): Mus musculus 
2020-11-23 | GSE152077 | GEO
UnknownTACI Isoforms Regulate Ligand Binding and Receptor Function.
Not available
S-EPMC6176016 | biostudies-literature
UnknownTNFRSF13B Variant-Induced TACI Dysregulation Underlies CAEBV Pathogenesis.
Not available
S-EPMC12830494 | biostudies-literature
Sort   by:  
 Page size