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MetabolomicsMicrobiome and metabolome features in treatment of early weaned piglets via multi-omics integration analyses across cohorts

BACKGROUND: Diarrhea is common in infants, particularly, children less than 2 years old. Intractable or protracted infancy diarrhea is typically associated with feeding intolerance and malabsorption that is lethal for newborns. This study aimed to evaluate the effectiveness of ba...

2024-02-01 | MTBLS9292 | MetaboLights
ProteomicsShiga toxin 2a induces mitochondrial damage, mitophagy and apoptosis via the interaction of Tom20 in Caco-2 cells
Shiga toxin type 2 (Stx2) is the main virulence factor produced by Stx-producing Escherichia coli (STEC) responsible for hemorrhagic colitis and the life-threatening sequela hemolytic uremic syndrome.
ORGANISM(S): Homo Sapiens 
2022-11-21 | PXD038256 |
UnknownDevelopment of a Novel Quinoline Derivative as a P-Glycoprotein Inhibitor to Reverse Multidrug Resistance in Cancer Cells.
Not available
S-EPMC6955663 | biostudies-literature
GenomicsCohort-Based Genome-Wide Association Study of Glioma (GliomaScan)

We conducted a new independent GWAS of adult glioma using 1,856 cases and 4,955 controls from 14 cohort studies belonging to the Cohort Consortium, 3 case-control studies, and 1 population-based case only study. Cases were newly diagnosed glioma [ICDO-3 codes 9380-9480 or equivalent], and control...

phs000652.v1.p1 | EGA
ProteomicsThe antibacterial mechanism of sertindole against Staphylococcus aureus
Clinically isolated MRSA strain was inoculated and cultured to exponential growth phase (OD600 at 0.5) in TSB and divided into two groups, the control group and the drug treated group. Sertindole was added to the drug treated group until a final concentration of 1/2× MIC reached, and DMSO added as L...
ORGANISM(S): Staphylococcus Aureus 
2022-07-14 | PXD035364 |
ProteomicsOuter membrane vesicles of carbapenem-resistant Acinetobacter baumannii derive enhanced inflammatory response
These findings illuminate dual mechanisms driving CRAB pathogenicity-extensive drug resistance combined with heightened host inflammatory response-and suggest novel intervention strategies targeting OMVs-mediated immune modulation.
ORGANISM(S): Acinetobacter Baumannii A424 
2026-01-23 | PXD073433 |
ProteomicsMLS0315771 S. aureus YUSA145 proteomics
Quantitative label-free proteomic analysis investigated the global proteomic response of S. aureus YUSA145 treated with 1/2 × MIC MLS0315771 during the exponential growth phase. The results were obtained after performing principal component analysis (PCA) on the raw data and excluding two replicates...
ORGANISM(S): Staphylococcus Aureus 
2026-01-24 | PXD073535 |
ProteomicsIdentification of candidate microRNA biomarkers of endometriosis in different bodily fluids
Endometriosis is a common gynecological condition that affects approximately 10% of women of reproductive age and up to half of those experiencing infertility. However, there is a lack of reliable noninvasive diagnostic tools for diagnosing endometriosis. This study aims to identify novel biomarkers...
ORGANISM(S): Homo Sapiens 
2025-11-17 | PXD070868 |
ProteomicsPlasma proteomic profiling discovers molecular features associated with upper urinary tract urothelial carcinoma
Upper tract urothelial carcinoma (UTUC) is often diagnosed late and exhibits poor prognosis. Only limited data are available concerning potential noninvasive biomarkers for disease monitoring. Here, we investigated the proteomic profile of plasma in 362 UTUC patients and 239 healthy control samples....
ORGANISM(S): Homo Sapiens 
2023-07-12 | PXD043774 |
ProteomicsProteomics dataset of COVID-19 and control patients
Proteomics dataset of COVID-19 and control patients
ORGANISM(S): Homo Sapiens 
2021-10-14 | PXD029023 |
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