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Very little is known about the genetic modulation of nictation, a host-finding strategy used by infective juveniles of many pathogenic nematodes, as well as a phoretic strategy of Caenorhabditis elegans dauers. We here use a mass spectrometry-driven approach to find neuropeptides involved in the mod...
ORGANISM(S): Steinernema carpocapsae 
2022-12-08 | PXD034629 | Pride
Neuropeptides constitute a vast and functionally diverse family of neurochemical signaling molecules, and are widely involved in the regulation of various physiological processes. The nematode C. elegans is well-suited for the study of neuropeptide biochemistry and function, as neuropeptide biosynth...
ORGANISM(S): Caenorhabditis elegans 
2018-03-12 | PXD008942 | Pride
The onset of sexual maturity involves dramatic changes in physiology and gene expression in many animals. A textbook example is the production of enormous amounts of yolk proteins destined for the nascent oocytes, termed vitellogenesis. We previously identified the rapidly evolving PBC-class Hox-cof...
ORGANISM(S): Caenorhabditis elegans 
2019-09-25 | PXD013584 | Pride
Many anthelmintics target the neuromuscular system, in particular by interfering with signalling mediated by classical neurotransmitters. Although peptidergic signalling has been proposed as a target of novel anthelmintics, current knowledge of the neuropeptide complement of many helminths is still ...
ORGANISM(S): Hymenolepis microstoma 
2022-06-13 | PXD033611 | Pride
Oviparous animals support reproduction via the incorporation of yolk as a nutrient source into the eggs. In Caenorhabditis elegans, however, yolk proteins seem dispensable for fecundity, despite constituting the vast majority of the embryonic protein pool and acting as carriers for nutrient-rich lip...
ORGANISM(S): Caenorhabditis elegans 
2023-04-12 | PXD041110 | Pride
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