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ProteomicsTent5a Immunoprecipitation in pancreatic beta cells
Wild Type Tent5a or catalytically inactive Tent5a was over-expressed and immunoprecipitated from INS-1E cell lysates. Binding partners were identified using LC-MS.
ORGANISM(S): Rattus norvegicus (Rat) 
2025-08-22 | PXD066929 | Pride
Lc-ms Immunoprecipitation Tent5a Pancreatic beta cells 
GenomicsTent5A osteoblasts directRNA
Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.
PRJEB39819 | ENA
GenomicsThe TENT5A–ATXN2 axis modulates cellular survival during heat stress.
The TENT5A–ATXN2 axis modulates cellular survival during heat stress.
PRJNA1369545 | ENA
TranscriptomicsThe TENT5A–ATXN2 axis modulates cellular survival during heat stress.
Stress conditions elicit the formation of different kinds of stress granules. The assembly and composition of heat-induced stress granules remain poorly characterized. Here, we show that the cytoplasmic RNA polyadenylases TENT5A regulate the formation and function of ATXN2-positive heat-induced stre...
ORGANISM(S): Mus musculus 
2026-07-10 | GSE311487 | GEO
UnknownTENT5A-associated osteogenesis imperfecta: long-term follow-up and molecular insights.
Not available
S-EPMC12202044 | biostudies-literature
UnknownRe-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines.
Not available
S-EPMC12095053 | biostudies-literature
ProteomicsTENT5A mediated cytoplasmic polyadenylation in osteoblast supports proper bone formation.
The bone formation, osteogenesis, is a very complex process in which osteoblasts play a crucial role. The primary function of theses terminally differentiated mesenchymal stem cells is the secretion of fibrillary, dense, highly crosslinked type 1 collagen. Herein we show that the TENT5A gene, which...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD020346 | Pride
Collagen Mice Lc-ms/ms 
Genomics
Polyadenylation of Insulin mRNA by Tent5a regulates pancreatic beta cell function
PRJNA1267696 | ENA
GenomicsTENT-5 C. elegans and TENT5A/C murine BMDM
TENT5 cytoplasmic non-canonical poly(A) polymerases regulate the innate immune response in animals
PRJEB40892 | ENA
ProteomicsTENT5 cytoplasmic non-canonical poly(A) polymerases regulate the innate immune response in animals
Innate immunity, the first line of host defense against pathogens, is tightly regulated both transcriptionally and post-transcriptionally. Here, through global transcriptome and proteome analyses in Caenorhabditis elegans, we uncover a modulation of the expression of secreted innate immunity effecto...
ORGANISM(S): Caenorhabditis elegans 
2022-05-31 | PXD023238 | Pride
Innate immunity Cytoplasmic polyadenylation Non-canonical polyadenylation Tent5 Direct rna sequencing Terminal nucleotidyltransferase C. elegans innate immunity 
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