Sort   by:  
 Page size 
MetabolomicsMulti-omics profiling identifies MAPK signaling suppression associated with tetracycline-induced root toxicity in soybean
Tetracycline (TC), a widely used veterinary antibiotic, is a pervasive emerging contaminant threatening crop production. Here, we employed integrated physiological, metabolomic, and transcriptomic analyses to decipher the response of soybean (Glycine max L.) to TC. While seed germination was unaffec...
2026-09-07 | MTBLS15077 | MetaboLights
TranscriptomicsTetracycline-treated Litomosoides sigmodontis vs. untreated control Litomosoides sigmodontis
The filarial nematodes Brugia malayi, Wuchereria bancrofti and Onchocerca volvulus cause elephantiasis, dermatitis and blindness, resulting in severe morbidity in developing countries. 1.3 billion people are at risk of infection. Targeting the essential Wolbachia endobacteria of filarial nematodes w...
ORGANISM(S): Litomosoides sigmodontis 
2010-04-07 | E-GEOD-20976 | biostudies-arrayexpress
ProteomicsE. coli EcAmb278 treated with tetracycline
Drug profiling exeriment to elucidate protein regulation upon treatment of a multi-drug resistant E.coli strain with tetracycline.
ORGANISM(S): Escherichia coli 
2017-01-06 | PXD003641 | Pride
Lc-ms Tetracycline Shotgun E. coli Label free 
ProteomicsProteome profiling of Bacillus subtilis stressed with the antibiotics tetracycline and chelocardin
Chelocardin is an atypical tetracycline and its mechanism of action is discussed controversially in literature. Therefore, we analyzed the bacterial response of Bacillus subtilis to chelocardin and as a control for classical tetracyclines to tetracycline by proteomic profiling. The induced marker pr...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2016-03-14 | PXD003439 | Pride
Bacillus subtilis tetracycline chelocardin 2d-page proteomics 
TranscriptomicsC. elegans gene expression in response to Salmonella enterica infection and recovery by Tetracycline treatment
(Part 1) Gene expression profiles of C. elegans in response to a 120 hour S. enterica infection. Synchronized larval stage 1 (L1) animals were exposed to S. enterica SL1344 for 36, 72, 96, or 120 hours. As an uninfected control, synchronized L1 animals were exposed to E. coli OP50 for 36 hours. (Par...
ORGANISM(S): Caenorhabditis elegans 
2014-07-26 | E-GEOD-54212 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hearts of tetracycline transactivator (tTA) transgenice mice and wild type mice to study the effects of tTA expression in the hearts.
This study was conducted using affymetrix microarrays. We were interested in determining the effects of tTA expression in the hearts of FVBN mice. We compared expression to wild type mice.
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-986 | biostudies-arrayexpress
TranscriptomicsTetracycline knock-down of Zcf11, the Ume6 orthologue in the human pathogenic yeast Candida glabrata
Zcf11 translation was put under the negative control of tetracycline. The transgenic strain was exposed to tetracycline for 2 or 4 hours to inhibit the expression of the Zcf11 protein and these transcriptomes were compared to RNA samples from the same strain with mock treatment.
ORGANISM(S): Saccharomyces cerevisiae 
2024-12-24 | E-MTAB-14305 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression
Analysis of C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dystrophy. Results of this s...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8312 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of A375 cells treated with tetracycline-based crosslinking probes, with and without competition by parent tetracyclines, to show specific binding of the tetracycline analogs Col-3 and doxycycline on rRNA substructures of the human ribosome
Upon finding that the tetracyclines COL-3 and doxycycline target unique rRNA substructures of the 80S ribosome (E-MTAB-7147), we confirmed these putative ribosomal binding sites by showing that tetracycline-based crosslinking probes are specifically competed from these rRNA structures by their paren...
ORGANISM(S): Homo sapiens 
2018-08-31 | E-MTAB-7161 | biostudies-arrayexpress
TranscriptomicsStable and inducible expression of Fbxo25 in Flp-In-293 cells: control vs. tetracycline treatment
Expression profile of human Flp-In-293-WT-FBXO25 or Flp-In-293-M-bM-^HM-^FF-FBXO25 cells comparing non treated cells vs. tetraciclyne treated for 24 and 48 hours. Flp-In-293-M-bM-^HM-^FF-FBXO25 cells when induced express the non functional protein (without F-box domain). The objective of the study ...
ORGANISM(S): Homo sapiens 
2012-05-14 | E-GEOD-37380 | biostudies-arrayexpress
Sort   by:  
 Page size