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Untargeted fecal metabolomics using UHPLC-MS/MS to analyze microbiota-dependent metabolic changes in C57BL/6 mice exposed to 6PPD-quinone (6PPD-Q) with/without antibiotic-mediated gut microbiota depletion. Key pathways include tryptophan and nicotinamide metabolism linked to intestinal barrier fu...

2026-09-15 | MTBLS14308 | MetaboLights
Lipids play an important role in energy storage, membrane structure stabilization and signaling. Parasitoids are excellent models to study lipidomics because a majority of them do not accumulate during their free-living life-stage. Studies on parasitoids have mostly focused on the changes in the lip...
2021-10-06 | MTBLS409 | MetaboLights
UVPD was implemented on an Orbitrap Q-Exactive plus equipped with a ESI/EP-MALDI. UVPD of MALDI generated ions was benchmarked against MALDI-ISD, MALDI-HCD and ESI-UVPD. MALDI UVPD outperformed MALDI HCD and ISD efficiently sequencing small proteins ions.
ORGANISM(S): Homo sapiens (Human) Equus caballus (Horse) 
2019-01-24 | PXD011526 | Pride
The quadrupole Orbitrap mass spectrometer (Q Exactive) has made a powerful proteomics instrument available in a benchtop format. It significantly boosted analyzable proteins per hour and has now evolved into a proteomics analysis workhorse for many laboratories. Here we describe the Q Exactive Plus ...
ORGANISM(S): Homo sapiens (Human) 
2014-11-10 | PXD001203 | Pride
Bipolar disorder (BD) shows strong heritability and distinct symptomatic subtypes. However, the molecular basis underlying subtype-specific features remains poorly understood. Here, we showed that Serinc2, a BD susceptibility gene encoding a L-serine transporter that regulates membrane lipid synthes...
2026-07-06 | MTBLS14954 | MetaboLights
The Chromosome-Centric Human Proteome Project (C-HPP) aims at finding existence evidence of missing proteins (MPs) at the early stage. Based on previous research, it has been proved that human testis tissue is suitable for further research of MPs because of its high gene expression level and high tr...
ORGANISM(S): Homo sapiens (Human) 
2016-09-30 | PXD004092 | Pride

Ultra-high-performance liquid chromatography (UHPLC) was conducted using a Vanquish UHPLC system (Thermo Fisher), coupled with a Q Exactive™ HF/Q Exactive™ HF-X mass spectrometer for liquid chromatography-mass spectrometry (LC-MS) analysis. To ensure...

2026-06-05 | MTBLS14159 | MetaboLights
Increasing number of studies report the relevance of protein Ser/Thr/Tyr phosphorylation in bacterial physiology, yet the analysis of this type of modification in bacteria still presents a considerable challenge. Unlike in eukaryotes, where tens of thousands of phosphorylation events likely occupy m...
ORGANISM(S): Escherichia coli 
2018-06-05 | PXD008211 | Pride
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