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ProteomicsData for Cross-platform Construction of Comprehensive Proteomic Database for Human Corneal Epithelial Cell
Comprenhensive proteomic analysis of HCEC using Trapped Ion Mobility Spectrometry Time-of-Flight Pro2, Orbitrap Fusion Lumos and ZenoTrap Time-of-Flight 7600 Mass Spectrometer
ORGANISM(S): Homo sapiens (Human) 
2025-03-24 | PXD059451 | Pride
Timstof Proteome Orbitrap Zenotof Human corneal epithelial cell 
ProteomicsProteoform analysis by mass spectrometry reveals post-translational processing of legumins and vicilins in chickpeas (Cicer arietinum L.)
The most abundant proteins in pulse seed, including chickpea (Cicer arietinum L.), are the 7S globulins (vicilins) and 11S globulins (legumins), which play key roles in plant reproduction and human nutrition and are also recognized as potential allergens. During seed maturation, legumins and vicilin...
ORGANISM(S): Cicer arietinum (Chickpea) (Garbanzo) 
2026-06-01 | PXD078377 | Pride
Orbitrap® mass spectrometry Legumins and vicilins Bottom-up and top-down approaches Chickpea proteins proteolysis N-glycosylated plant proteins 
MetabolomicsProteomic analysis of osteocyte line (MLO-Y4) with knockout of cystic fibrosis transmembrane conductance regulator (CFTR) or chloride deprivation treatment

Mass spectrometry–based proteomic analysis of an osteocyte line, MLO-Y4, was conducted to profile global protein expression changes under two experimental settings, 1) CRISPR-Cas9-based knockout of CFTR versus wild-type; 2) Cl- deprivation versus normal extracellular medium.

2026-03-27 | MTBLS14165 | MetaboLights
ProteomicsNuclear Condensation of NUP98-Fusion Proteins drives leukemogenic gene expression NUP98-fusion protein drive oncogenic gene expression via nuclear/biomolecular condensation
NUP98-fusion proteins cause leukemia via unknown molecular mechanisms. All NUP98-fusion proteins share an intrinsically disordered region (IDR) featuring >35 repeats of Phenylalanine-Glycine (FG) in the NUP98 N-terminus. Conversely, C-terminal NUP98-fusion partners often have critical functions in g...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD022518 | Pride
Aml Ap-ms Fusion protein Nup98 Bicon-ms Condensate 
ProteomicsComprehensive identification of Ubiquitin-like 3 (UBL3)-interacting proteins in mouse brain
Each protein extract from the cortex of Ubl3+/+ and Ubl3Tg/+ male mice (9-10-week-old, n=3, 3) was incubated with 30 μL of NeutrAvidin Agarose (ThermoFisher, 29202) for 18 h at 4 °C and subjected to mass spectrometry using previously reported methods (Ageta et al., Nat Commun 2018, PMID: 30258067). ...
ORGANISM(S): Mus Musculus (mouse) 
2024-11-20 | PXD047087 | JPOST Repository
ProteomicsSpecific post-translational modifications of VDAC3 in ALS-SOD1 model cells identified by High-Resolution Mass Spectrometry
Damage induced by oxidative stress is a key driver of the selective motor neuron death in amyotrophic lateral sclerosis (ALS). Mitochondria are among the main producers of ROS, but they also suffer particularly from their harmful effects. Voltage-dependent anion-selective channels (VDACs) are the mo...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD036728 | Pride
Deamidation  amyotrophic lateral sclerosis  voltage dependent anion channel  post-translational modifications  mitochondria  ros  mass spectrometry analysis  orbitrap fusion tribrid  neurodegeneration  sod1. 
ProteomicsProteomic Analysis of the Shandrin Mammoth by EVA Technology and High-Resolution Mass Spectrometry: What is its Gut Telling Us?
The investigation about archaeological samples, which are of inestimable value, requires minimally destructive or nondestructive sampling techniques. One of the most promising and recent non-invasive techniques is known under the acronym EVA, an ethylene vinyl acetate film which avoids contamination...
ORGANISM(S): Mammuthus sp. 
2021-11-03 | PXD025518 | Pride
Paleoproteomic Mammoth High-resolution mass spectrometry Non-invasive technique Deamidation 
ProteomicsThe GF-NEO Discovery Platform: A Systems-Level Approach to Analyzing and Validating Fusion Neoantigens in Pediatric Cancer
Gene fusions (GFs) are critical events in pediatric oncology, often serving as oncogenic drivers. However, fusion proteins and their derived neoantigens (GF-NEOs) remain underexplored for targeted immunotherapy. We developed ProteoFusioNEO, a computational tool for in silico translation of transcrip...
ORGANISM(S): Homo sapiens (Human) 
2025-11-26 | PXD063253 | Pride
ProteomicsData for Cross-platform Construction of Comprehensive Proteomic Database for Human Corneal Epithelial Cell
Comprenhensive proteomic analysis of HCEC using Trapped Ion Mobility Spectrometry Time-of-Flight Pro2, Orbitrap Fusion Lumos and ZenoTrap Time-of-Flight 7600 Mass Spectrometer
ORGANISM(S): Homo sapiens (Human) 
2024-11-03 | PXD055275 | Pride
Fuaion Hcec Timstof Zenotof 
ProteomicsA High Resolution Mass Spectrometry Study Reveals the Potential of Disulfide Formation in Human Mitochondrial Voltage-Dependent Anion Selective Channel Isoforms (hVDACs)
The voltage-dependent anion-selective channels (VDACs), also known as eukaryotic porins, are pore-forming proteins which allow the passage of ions and small molecules across the outer mitochondrial membrane (OMM). They are involved in complex interactions regulating organelle and cellular metabolism...
ORGANISM(S): Homo sapiens (Human) 
2020-03-09 | PXD017482 | Pride
Cysteine over-oxidation  mitochondria  orbitrap fusion tribrid  hydroxyapatite  mitochondrial intermembrane space  outer mitochondrial membrane  post-translational modification 
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