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ProteomicsHigh-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform
Single cell proteomics data from three murine cell lines (Raw, SVEC4-10, C10) and HeLa cell lysate. Samples were digested with trypsin and labeled with TMT 10-Plex on a small scale using nanoPOTS, followed by LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-07-19 | MSV000084110 | MassIVE
UnknownAnalysis of isobaric quantitative proteomic data using TMT-Integrator and FragPipe computational platform.
Not available
S-EPMC12154698 | biostudies-literature
ProteomicsEvaluation of differential peptide loading on TMT-based proteomic and phosphoproteomic data quality
Investigating the impacts on MS data quantitation reproducibility when loading differential amounts of peptides, ranging from 20 to 400 ug, across channels of TMT 11 multiplexes. PTRC_Exp9 files represent global proteome and phosphoproteome data generated from PBMCs isolated from AML patients, acqui...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-05 | MSV000086417 | MassIVE
ProteomicsTMT-based quantitative proteomic analysis of SAHA-treated human HeLa cells
We performed a TMT-based quantitative proteomic analysis of SAHA-perturbed human HeLa cells using advanced RTS platform on Orbitrap Eclipse Tribrid MS system.
ORGANISM(S): Homo Sapiens (human) 
2023-06-09 | PXD038681 | JPOST Repository
ProteomicsA causal model of ion interference enables assessment and correction of ratio compression in multiplex proteomics
We thoroughly characterize isobaric labeling (TMT)-associated reporter ion interference at the MS2 level using a defined two-proteome experimental system with known ground truth. We discover remarkably poor agreement between the apparent precursor purity in the isolation window and the actual level ...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2023-12-19 | PXD040449 | Pride
Ion interference Tmt Ratio compression Isobaric label 
UnknownOptimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer's disease biomarkers.
Not available
S-EPMC9107710 | biostudies-literature
ProteomicsTMT analysis of tissue proteomics in bevacizumab-resistant xenograft tumor tissuein nude mice
TMT proteomics was used to detect the difference in protein expression of bevacizumab-resistant xenograft tumor tissue in nude mice.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD030202 | Pride
Lc-ms Colorectal cancer I.e.human 
UnknownExpanding the Landscape of Aging via Orbitrap Astral Mass Spectrometry and Tandem Mass Tag (TMT) Integration.
Not available
S-EPMC11702764 | biostudies-literature
ProteomicsQuantitative Global and Phospho-proteomics analysis of rapamycin-treated human SU-DHL-4 cells by LC-MSMS
Global protein profiling and global phospho-protein profiling in human diffuse large B cell lymphoma cell line SU-DHL-4 treated with Rapamycin at two time points compared with DMSO control was performed by Poochon Scientific using the TMT-18plex labeling based quantitative proteomics method and liqu...
ORGANISM(S): Homo sapiens (Human) 
2025-09-03 | PXD067812 | Pride
Lc-msms Global protein profiling Rapamycin Su-dhl-4 Tmt multiplex Global phospho-protein profiling Dlbcl 
UnknownAAV9-TAZ Gene Replacement Ameliorates Cardiac TMT Proteomic Profiles in a Mouse Model of Barth Syndrome.
Not available
S-EPMC6369239 | biostudies-literature
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