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ProteomicsCompetition or indifference: Neutron-Encoding to profile linkage selectivity of deubiquitinating enzymes
This data set contains all raw data files in the mzXML (for LC-MS data) format that belongs to the manuscript "Competition or indifference: Neutron-Encoding to profile linkage selectivity of deubiquitinating enzymes" by Bianca D. M. van Tol, Bjorn R. van Doodewaerd, Guinevere S. M. Lageveen-Kammeije...
ORGANISM(S): Synthetic Ubiquitins 
2022-10-05 | MSV000090455 | MassIVE
UnknownIndividualised immunosuppression with intravenously administered donor-derived modified immune cells compared with standard of care in living donor kidney transplantation (TOL-2 Study): protocol for a multicentre, open-label, phase II, randomised controlled trial.
Not available
S-EPMC9660568 | biostudies-literature
TranscriptomicsIndices of Tolerance (IOT): Cross-platform biomarkers that identify kidney transplant tolerance
Being able to identify patients in whom immunological tolerance has been established or is developing would allow an individually tailored approach to post-transplant management of kidney allograft recipients. Ex vivo immunological monitoring was performed on samples from five groups of European ren...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-14655 | biostudies-arrayexpress
UnknownAssessment of Motor Planning and Inhibition Performance in Non-Clinical Sample-Reliability and Factor Structure of the Tower of London and Go/No Go Computerized Tasks.
Not available
S-EPMC8615804 | biostudies-literature
TranscriptomicsMicroarray Analysis of the Developing Murine Prefrontal Cortex
Abnormal development of the prefrontal cortex (PFC) is associated with a number of neuropsychiatric disorders that have an onset in childhood or adolescence. Although the basic laminar structure of the PFC is established in utero, extensive remodeling continues into adolescence. To map the overall p...
ORGANISM(S): Mus musculus 
2006-05-15 | E-GEOD-4675 | biostudies-arrayexpress
ProteomicsNeural stem cells traffic functional mitochondria via extracellular vesicles to correct mitochondrial dysfunction in target cells.
Neural stem cell (NSC) transplantation induces recovery in animal models of central nervous system (CNS) diseases. Although the replacement of lost endogenous cells was originally proposed as the primary healing mechanism of NSC grafts, it is now clear that transplanted NSCs operate via multiple mec...
ORGANISM(S): Homo sapiens (Human) 
2021-03-16 | PXD024368 | Pride
Exosomes 
ProteomicsQuantitative proteomics analysis of lytic KSHV infection in human endothelial cells reveals novel targets of viral immune modulation
Kaposi’s Sarcoma associated herpesvirus (KSHV) is an oncogenic human virus and leading cause of mortality in HIV infection. Reactivation of KSHV from latent to lytic stage infection initiates a cascade of viral gene expression, and here we show how these changes remodel the host cell proteome to ena...
ORGANISM(S): Homo sapiens (Human) Human gammaherpesvirus 8 
2021-08-23 | PXD021387 | Pride
Kshv 
ProteomicsQuantitative proteomics analysis of lytic KSHV infection in human endothelial cells reveals novel targets of viral immune modulation
Kaposi’s Sarcoma associated herpesvirus (KSHV) is an oncogenic human virus and leading cause of mortality in HIV infection. Reactivation of KSHV from latent to lytic stage infection initiates a cascade of viral gene expression, and here we show how these changes remodel the host cell proteome to ena...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 8 strain rKSHV.219 
2022-05-26 | PXD017365 | Pride
Proteomics Kshv Immune modulation 
ProteomicsMassive Proteome Remodelling by HIV Vpr
Viruses target host proteins for degradation to enhance their replication and transmission, and identifying these targets has provided key insights into the host-pathogen interaction1-3. Here, we use complementary unbiased mass spectrometry-based approaches to dissect the widespread proteomeic remod...
ORGANISM(S): Homo sapiens (Human) 
2019-05-01 | PXD013221 | Pride
Hiv Tmt Vpr 
ProteomicsEROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
The phagocyte NADPH oxidase is critical for host defence, and EROS (Essential for Reactive Oxygen Species) protein is indispensable for expression of its gp91phox-p22phox heterodimer. EROS deficiency in humans is a recently described cause of chronic granulomatous disease (CGD), but its mechanism of...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD025149 | Pride
Nox family Inflammasome Nadph oxidase Ost complex Chaperone T cells P2x receptor Er 
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