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BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterized by hyperandrogenism, ovarian dysfunction and polycystic ovarian morphology. Gut microbiota dysbiosis and metabolite are associated with PCOS clinical parameters. Yulin Tong Bu formula (YLT...

2023-02-02 | MTBLS6736 | MetaboLights
Global CO2 level presently recorded at 400 ppm is expected to reach 550 ppm in 2050, an increment likely to impact plant growth and productivity. Using targeted LC-MS and GC-MS platforms we quantified 229 and 29 metabolites, respectively in a time-course study to reveal short-term responses to diffe...
2017-04-25 | MTBLS311 | MetaboLights
As a ubiquitous bacterial secondary messenger, c-di-GMP plays key regulatory roles in processes like bacterial motility and transcription regulation. We found that c-di-GMP had impact on lysine acetylation level. To further investigate the regulation role, we performed a quantitative analysis of E. ...
ORGANISM(S): Escherichia coli 
2019-06-17 | PXD010558 | Pride
To determine whether c-di-GMP could affect CobB-dependent deacetylation in a global setting, we applied Stable Isotope Labeling with Amino acids in Cell culture (SILAC) coupled with MS to quantitatively compare the levels of protein acetylation in WT, ΔcobB and ΔdgcZ cells.
ORGANISM(S): Escherichia coli 
2019-06-17 | PXD013292 | Pride
To establish the protein expression profile of Ba168, a high-resolution LC-MS/MS proteomic analysis was performed. A total of 1155 proteins were identified from 5233 unique peptides. GO and KEGG analysis revealed that a majority of the proteins were associated with biosynthesis and carbon metabolism...
ORGANISM(S): Bacillus amyloliquefaciens 
2022-08-11 | PXD014057 | Pride
Membrane proteins play critical roles between the tumor cells and the extra-cellular matrix (ECM) during metastasis. In this study, we performed quantitative proteomic analysis of membrane proteins from two human giant-cell lung carcinoma cell strains, low- (95C) and high-(95D) metastatistic cell li...
ORGANISM(S): Homo sapiens (Human) 
2020-08-18 | PXD016912 | Pride
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