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ProteomicsAcetylome analysis of acetylation providing new insight into sclerotial generation in medicinal fungus Polyporus umbellatus
Polyporus umbellatus sclerotia are medicinal tissue, but little is known about acetylome of sclerotia generated from hyphae. Acetylated peptides in P. umbellatus were enriched by anti-acetyl-lysine antibody beaded agarose and DDA data were acquired by AB Triple TOF 5600+. Raw data were analyzed by P...
ORGANISM(S): Polyporus umbellatus GSX09 
2022-05-20 | PXD031195 | Pride
Ab triple tof5600+ Polyporus umbellatus 
ProteomicsCompatibility of distinct label-free proteomic workflows in absolute quantification of proteins linked to the oocyte quality in human follicular fluid (the Triple-Quad TOF workflow)
We present a comprehensive analysis of human follicular fluid proteome by comparing several strategies of sample preparation, mass spectrometry analysis, and data processing, resulting in the identification of 1638 proteins. We devised two separate label-free quantitative workflows, termed after the...
ORGANISM(S): Homo sapiens (Human) 
2021-07-23 | PXD024223 | Pride
Lc-ms/ms Oocyte quality control Human follicular fluid Oocyte maturity Total protein approach Swath-ms Proteome Blastocyst development 
MetabolomicsKidney protective effect of fermented celery polysaccharides and Eubacterium rectale in diabetic rats

This study aimed to investigate the protective effects of non-fermented celery polysaccharides (NFCP), fermented celery polysaccharides (FCP), Eubacterium rectale (ER), and their combined intervention (ER+FCP) on Type 2 diabetes (T2D)-related kidney injury in a rat model, using untargeted urinary...

2026-03-02 | MTBLS13958 | MetaboLights
MetabolomicsBacteroides uniformis degrades β-glucan to promote Lactobacillus johnsonii improving indole-3-lactic acid levels in alleviating colitis

The gut microbiota plays a crucial role in the onset and progression of inflammatory bowel disease (IBD). β-glucan (BG), a soluble dietary fiber widely present in oats, barley, fungi, yeast and some bacteria, has multiple bioactive properties such as mitigating intestinal inflammation; however, t...

2024-02-12 | MTBLS8950 | MetaboLights
ProteomicsQuantitative proteomic analysis reveals molecular adaptations in the hippocampal synaptic active zone of chronic mild stress-unsusceptible rats
Background: While stressful events are recognized as an important cause of major depressive disorder (MDD), some individuals exposed to life stressors maintain normal psychological functioning. Although the molecular mechanism(s) underlying this phenomenon remain unclear, abnormal transmission and p...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-11-05 | PXD002540 | Pride
Rat hippocampus Triple tof 5600 Itraq Lc-ms/ms 
ProteomicsProteomics profiling of pediatric choroid plexus tumors
Aggresome is a para nuclear inclusion body that functions as a storage compartment for misfolded proteins. Our previous work revealed the presence of aggresomes in pediatric choroid plexus tumors (CPT). CPTs are rare neoplasms comprised of three pathological subgroups; choroid plexus carcinoma (CPC)...
ORGANISM(S): Homo sapiens (Human) 
2021-02-11 | PXD021076 | Pride
Human Carcinoma Cancer Choroid plexus Tissue Pappiloma Atypical Tumor Pediatric 
ProteomicsIdentify Novel Iron–Transporting Proteins in Streptococcus pneumoniae
Streptococcus pneumoniae (S. pneumoniae) is a major human pathogen causing morbidity and mortality worldwide. Efficiently acquiring iron from the environment is critical for S. pneumoniae to sustain growth and cause infection. There are only three known iron-uptake systems in Streptococcal species r...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2018-10-26 | PXD003313 | Pride
Streptococcus pneumoniae Iron–transporting proteins Proteomics 
ProteomicsA Comprehensive map and functional annotation of human pituitary and thyroid proteome
A Comprehensive map and functional annotation of human pituitary and thyroid proteome
ORGANISM(S): Homo sapiens (Human) 
2017-07-07 | PXD006471 | Pride
Thyroid Pituitary Human 
MetabolomicsMetabolomics Study of Serum and Urine Samples Reveals Metabolic Pathways and Biomarkers Associated with Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is a common medical condition among women and involves complicated diagnostics and controversial surgical management. The exact molecular mechanism underlying POP is poorly understood, especially at the metabolism level. To explore the metabolic mechanism underlying POP a...
2019-08-14 | MTBLS1033 | MetaboLights
ProteomicsProteoWizard Signal Processing Evaluation: ABSCIEX Triple TOF 5600 QqToF, Ecoli
3 replicates collected in profile mode (MS and MS/MS) for evaluation of ProteoWizard signal processing.
ORGANISM(S): Ecoli 
2014-08-24 | MSV000078824 | MassIVE
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