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ProteomicsProteomics of NGF-TrkA signaling dynamics in neuroblastoma cells
We used quantitative mass spectrometry-based proteomics to unravel global nerve growth factor (NGF)-induced TrkA signaling dynamics at the interactome, phosphoproteome and proteome level. A tetracycline-inducible system for TrkA expression was generated in the human neuroblastoma cell line, SH-SY5Y....
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080834 | MassIVE
ProteomicsProteomics of NGF-TrkA signaling dynamics in neuroblastoma cells
We used quantitative mass spectrometry-based proteomics to unravel global nerve growth factor (NGF)-induced TrkA signaling dynamics at the interactome, phosphoproteome and proteome level. A tetracycline-inducible system for TrkA expression was generated in the human neuroblastoma cell line, SH-SY5Y....
ORGANISM(S): Homo sapiens (Human) 
2015-05-06 | PXD001115 | Pride
Neuroblastoma Phosphoproteome Mass spectrometry Silac Ngf Proteome Trka Interactome 
ProteomicsProteomics characterization of NTRK1/TrkA signaling in neuroblastoma cells reveals intra-nuclear aggregation of Lamin A/C
Simple Summary: Neuroblastoma (NB) accounts for 15% of all cancer related deaths of children. While amplification of the Myc-N proto-oncogene (MYCN) is a major driver of NB, expression of the neurotrophin receptor, NTRK1/TrkA, has been shown to associate with an excellent outcome. MYCN down-regulate...
ORGANISM(S): Homo sapiens (Human) 
2021-11-11 | PXD026876 | Pride
Neuroblastoma Mycn Nuclear foci Trka Ntrk1 
ProteomicsProteomics characterization of NTRK1/TrkA signaling in neuroblastoma cells reveals intra-nuclear aggregation of Lamin A/C
Simple Summary: Neuroblastoma (NB) accounts for 15% of all cancer related deaths of children. While amplification of the Myc-N proto-oncogene (MYCN) is a major driver of NB, expression of the neurotrophin receptor, NTRK1/TrkA, has been shown to associate with an excellent outcome. MYCN down-regulate...
ORGANISM(S): Homo sapiens (Human) 
2021-11-11 | PXD026913 | Pride
Neuroblastoma Mycn Nuclear foci Trka Ntrk1 
TranscriptomicsTranscription profiling of human neuroblastoma SH-SY5Y/TrkA cells infected with dnEgr-expressing adenovirus (SH-SY5Y/TrkA-dnEgr) or EGFP-expressing control adenovirus (SH-SY5Y/TrkA-EGFP)
Nerve growth factor (NGF) is a neurotrophin that plays an important role in regulating the survival, growth, and differentiation of sympathetic neurons. Many in vitro studies indicate that Egr transcription factors are coupled to NGF signaling and are essential signaling mediators of NGF-dependent ...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2864 | biostudies-arrayexpress
GenomicsCharacterization of S. mitis trkA
Characterization of S. mitis trkA
PRJEB87292 | ENA
ProteomicsCharacterizing protein phosphorylation downstream of the TrkA receptor
Phosphorylation twenty minutes after stimulation of the TrkA receptor was characterized in PC12 (rat) cells. The study was performed using chimeric receptors, where the endodomain of TrkA was fused to the extracellular domain of PDGFR. As PDGFR (and PDGF) are not expressed in these cells, addition ...
2013-07-11 | MSV000078461 | MassIVE
GenomicsNerve Growth Factor (NGF) drives ILC2 pro-tumoral functions - bulk RNA sequencing of human TRKA+ and TRKA- ILC2s
Nerve Growth Factor (NGF) drives ILC2 pro-tumoral functions - bulk RNA sequencing of human TRKA+ and TRKA- ILC2s
PRJNA1368597 | ENA
GenomicsEffect of deletion of trkA on gene expression of Porphyromonas gingivalis W83
Effect of deletion of trkA on gene expression of Porphyromonas gingivalis W83
PRJNA866854 | ENA
GenomicsInfluenza A virus activates Tropomyosin receptor kinase A (TrkA) signaling to promote viral replication and lung inflammation
Influenza A virus activates Tropomyosin receptor kinase A (TrkA) signaling to promote viral replication and lung inflammation
PRJNA841344 | ENA
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