Trna variants - OmicsDI

Show results for

Unknown (583)
Genomics (94)
Transcriptomics (79)
Proteomics (34)
Other (11)

Organisms

Homo sapiens (67)
Mycobacterium tuberculosis SP7 (29)
Mycobacterium tuberculosis SP10 (29)
Mycobacterium tuberculosis SP13 (29)
Mycobacterium tuberculosis SP22 (29)
Chlamydomonas reinhardtii (29)
Enterococcus mundtii CRL35 (29)
Oncorhynchus tshawytscha (29)
Pseudomonas canadensis (29)
Mus musculus (18)
Saccharomyces cerevisiae (7)
Drosophila melanogaster (5)
Sus scrofa (3)
Danio rerio (3)
Glycine max (2)
Gallus gallus (2)
Severe acute respiratory syndrome-related coronavirus (1)
West Nile virus (1)
Saccharomyces paradoxus (1)
Cucumis melo (1)
Leishmania major (1)
Neurospora crassa (1)
synthetic construct (1)
Medicago truncatula (1)
Zea mays (1)
Solenopsis invicta (1)
Schizosaccharomyces pombe (1)
Heterodera schachtii (1)
Rattus norvegicus (1)
Arabidopsis thaliana (1)

Organisms

Homo sapiens (30)
Mus musculus (6)
Saccharomyces cerevisiae (3)
Escherichia phage T5 (1)
Drosophila melanogaster (1)
Saccharomyces cerevisiae BY4741 (1)
Danio rerio (1)

Repository

biostudies-arrayexpress (64)
ENA (64)
geo (37)
pride (29)
EGA (19)
PAXDB (3)
GPMDB (1)
jPOST (1)
MassIVE (1)

Tissue

Cell culture (3)
Brain (2)
Whole body (2)
Melanocyte of skin (1)
Haploid cell (1)
HEK-293 cell (1)
Medulloblastoma cell (1)
Early embryonic cell (1)
HeLa cell (1)
Fibroblast (1)
Permanent cell line cell (1)

Disease

Breast cancer (1)
Not Available (1)
Skin cancer (1)
Charcot-Marie-Tooth disease (1)
Cancer (1)
Neuroblastoma (1)
Disease free (1)

Technology Type

Mass Spectrometry (29)
Shotgun proteomics (10)
Data-dependent acquisition (8)
Bottom-up proteomics (8)
Affinity purification coupled with mass spectrometry proteomics (4)
SWATH MS (3)
Data-independent acquisition (3)
Gel-based experiment (3)
Illumina 15K (2)
SRM/MRM (2)
Top-down proteomics (2)
Illumina HumanExome-12v1_A (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (2)
NextSeq 500 (2)
G2565BA DNA microarray scanner [Agilent] (1)
None (1)
TruSeq® Nano (1)
GridION (1)
Ion Torrent S5 XL (1)
NextSeq 550 (1)
Illumina HiSeq 4000 (1)
Instrument (1)
Q Exactive (1)

Publication Date

2025 (22)
2024 (13)
2021 (11)
2010 (11)
2011 (9)
2023 (8)
2015 (8)
2013 (8)
2026 (8)
2014 (7)
2012 (6)
2022 (4)
2020 (4)
2016 (3)
2018 (3)
2019 (2)
2009 (2)
2007 (2)
2005 (2)
2008 (1)
2006 (1)

UNIPROT ID/AC

E0CYZ8_MOUSE (3)
TCL1A_MOUSE (3)
A14EL_MOUSE (3)
TSX_MOUSE (3)
ATG12_MOUSE (3)
RPAB2_MOUSE (3)
DPPA4_MOUSE (3)
S1PBP_MOUSE (3)
ZN287_MOUSE (3)
RPP25_MOUSE (3)
TCAL8_MOUSE (3)
DPA5A_MOUSE (3)
F10C1_MOUSE (3)
SKA2_MOUSE (3)
TYDP2_MOUSE (3)
RBIS_MOUSE (3)
SPC25_MOUSE (3)
GON7_MOUSE (3)
PALM3_MOUSE (3)
CBPC3_MOUSE (3)
BICRL_MOUSE (3)
MTF1_MOUSE (3)
RTEL1_MOUSE (3)
AEBP2_MOUSE (3)
CB076_MOUSE (3)
RN138_MOUSE (3)
AF10_MOUSE (3)
PCGF5_MOUSE (3)
GEMI_MOUSE (3)
RNF12_MOUSE (3)

First Public Date

2025 (15)
2024 (14)
2026 (8)
2021 (8)
2020 (5)
2023 (4)
2022 (3)
2019 (3)
2018 (2)
2016 (1)
2014 (1)

Classification

viruses (1)

Study type

Transcription profiling by array (20)
RNA-seq of coding RNA (13)
RNA-seq of non coding RNA (11)
ChIP-seq (5)
Transcription profiling by tiling array (3)
Other (3)
ChIP-chip by tiling array (2)
Comparative genomic hybridization by array (2)
Cell line - High-throughput sequencing (1)
ChIP-chip by array (1)
DNA-seq (1)
Genotyping by high throughput sequencing (1)

Release Date

2025 (71)
2024 (57)
2023 (55)
2021 (55)
2022 (54)
2019 (49)
2020 (48)
2018 (41)
2016 (32)
2015 (30)
2014 (23)
2013 (20)
2017 (20)
2011 (16)
2010 (15)
2012 (12)
2009 (11)
2007 (7)
2026 (7)
2006 (6)
2005 (4)
2008 (3)
2000 (3)
2004 (2)
2003 (2)
2001 (2)
2002 (1)
1999 (1)

Lab affiliation

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA (2)
Lab Head, UQ Diamantina Institute,The University of Queensland (2)
Department of Genome Sciences, University of Washington, Seattle, USA (2)
Institute of Bioengineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, China (1)
Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada. Department of Chemistry, The University of Western Ontario, London, Ontario, Canada. (1)
Department of Cell Biology and Molecular Genetics University of Maryland (1)
1.Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland. 2.Department for BioMedical Research, University of Bern, 3008 Bern, Switzerland. 3. Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Dublin D04 V1W8, Ireland. (1)
Department of Biochemistry, Department of Chemistry, The University of Western Ontario, London, Ontario, Canada (1)
University of Western Ontario, Canada, Department of Biochemistry (1)
Department of Genome Sciences, University of Washington (Seattle) (1)
Professor and Chair of Chemical Biology, Peking-Tsinghua Center for Life Sciences Peking University, Beijing, China. Associate Editor, ACS Chemical Biology (1)
Associate Professor of Biochemistry Schulich School of Medicine and Dentistry Scientist, Children’s Health Research Institute (CHRI) Medical Sciences Building 358 Western University London, Ontario N6A 5C1, Canada (1)
Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL 33458, USA (1)
Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada. 2 Bioinformatic Solutions Inc., Waterloo, Ontario, Canada. Department of Chemistry, The University of Western Ontario, London, Ontario, Canada. (1)
Dept of Biochemistry, Medical Sciences Building, Schulich School of Medicince and Dentistry, University of Western Ontario, London, ON, Canada (1)
Division of Oncogenomics, Oncode institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, the Netherlands (1)
Department of Genome Science, University of Washington, USA (1)
Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada. (1)
Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716 USA (1)
Department of Genome Sciences, University of Washington, Seattle, WA, USA (1)
Center for Medical Biochemistry, Max Perutz Labs, Medical University of Vienna, Vienna BioCenter(VBC), Austria (1)
Quantitative Proteomics & Proteome Center Tuebingen Interfaculty Institute for Cell Biology University of Tuebingen Tuebingen Germany (1)
Institute of Bioengineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, China (lab head) (1)
Department of Genome Science, University of Washington, Seattle, USA (1)
Department of Biochemistry, The University of Western Ontario, London, Ontario N6A 5C1 (1)
Head of the Curie Institute Mass Spectrometry Platform (1)

Previous page
1 / 81
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 81
Next page

Sort by:

Relevance

Page size

Quantifying mistranslation from alanine tRNA anticodon variants in S. cerevisiae

Transfer RNAs (tRNAs) maintain translational fidelity through strict charging by their cognate aminoacyl-tRNA synthetase and codon:anticodon base pairing with the mRNA at the ribosome. Mistranslation occurs when an amino acid not specified by the genetic code is incorporated into a protein. Since al...

ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)

2023-10-02 | PXD038242 | Pride

The Translin-TRAX complex/C3PO is a ribonuclease in tRNA processing

The endogenous RNA substrates of Translin-TRAX complexes (also known as C3POs) and how they regulate diverse biological processes remain unknown. Here we show that Translin and TRAX do not play a significant role in RNAi in the filamentous fungus Neurospora crassa. Instead, the Neurospora C3PO compl...

ORGANISM(S): Neurospora crassa

2012-07-30 | E-GEOD-38334 | biostudies-arrayexpress

NGS of West Nile viruses replicating in the presence of SLA RNAs or tRNA controls

West Nile infectious clones were transfected with either SLA or tRNA. Viral RNA was extracted on days 3 and 4 post-transfection for sequencing. Shannon entropy and single nucleotide variants were analyzed to compare the samples.

ORGANISM(S): West Nile virus

2025-07-15 | E-MTAB-14867 | biostudies-arrayexpress

Mistranslation from endogenous tRNA variants in human pan-genome cell lines

Errors in protein synthesis are thought to be rare, yet cells representing the diversity of life tolerate greatly elevated levels of error. One source of translation error in humans are anticodon mutations in transfer RNAs (tRNAs). We found a tRNA Ser AGA -2-3 variant (G35A) that occurs in 2% of the...

ORGANISM(S): Homo sapiens (Human)

2026-02-23 | PXD064886 | Pride

Mistranslation Trna variants Translation error

Detecting mistranslation in yeast expressing tRNA variants

Mistranslation, the mis-incorporation of an amino acid not specified by the “standard” genetic code, occurs in all cells. tRNA variants that increase mistranslation arise spontaneously and engineered tRNAs can achieve mistranslation frequencies approaching 10% in yeast and bacteria. The goal of this...

ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)

2021-05-17 | PXD025934 | Pride

Mistranslation Lc-msms Yeast Trna variants

Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C

Small, non-coding RNAs control gene expression post-transcriptionally and play important roles in virus-host interactions. Within the liver, the microRNA (miRNA) miR-122 is essential for replication of hepatitis C virus (HCV), while repression of miR-148a by hepatitis B virus (HBV) may enhance tumor...

ORGANISM(S): Homo sapiens

2014-12-18 | E-GEOD-57381 | biostudies-arrayexpress

Quantification of proline to serine mistranslation in a Saccharomyces cerevisiae strain expressing an inducible tRNA variant

Altering the genetic code for applications in synthetic biology and genetic code expansion involves engineered tRNAs that incorporate amino acids that differ from what is defined by the “standard” genetic code. Since these engineered tRNA variants can be lethal due to proteotoxic stress, regulating ...

ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)

2021-11-03 | PXD028496 | Pride

Yeast Inducible Mistranslation Trna variants

Characterizing the interactome of human Arginyl-tRNA Synthethase

Prior work revealed nuclear-localized aminoacyl-tRNA synthetases (aaRSs) that checked newly synthesized tRNAs for charging before export to the cytoplasm. To reveal other functions, we sought to identify nuclear proteins that interact with arginyl-tRNA synthetase (ArgRS) in the nucleus. Serine/Arg...

ORGANISM(S): Homo sapiens (Human)

2023-04-14 | PXD015692 | Pride

Arginine Trna syntethase Trna

Identification of proline to serine mistranslation in Drosophila melanogaster pupae

Transfer RNAs (tRNAs) are the adaptor molecules required for reading of the genetic code and the accurate production of proteins. tRNA variants can lead to genome-wide mistranslation, the misincorporation of amino acids not specified by the standard genetic code, into nascent proteins. While genome ...

ORGANISM(S): Drosophila melanogaster (Fruit fly)

2021-09-18 | PXD028498 | Pride

Pupae Mistranslation Trna variants Drosophila melanogaster

Mistranslating tRNA variants impact on the proteome and phosphoproteome of Saccharomyces cerevisiae – phosphoproteome DDA and DIA data

Mutations in tRNAs can lead to mis-incorporation of an amino acid into a growing polypeptide chain that differs from what is specified by the mRNA in a process known as mistranslation. As mistranslating tRNAs modify how the genetic message is decoded, they have potential as therapeutic tools to trea...

ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)

2025-11-18 | PXD068388 | Pride

Phosphoproteome Translation fidelity Trnas Saccharomyces cerevisiae Mistranslation Yeast

Previous page
1 / 81
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 81
Next page

Sort by:

Relevance

Page size

802 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

UNIPROT ID/AC

First Public Date

Classification

Study type

Release Date

Lab affiliation

Tags

OmicsDI is part of the ELIXIR infrastructure

Tweets