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ProteomicsProteomics Reveals Extracellular Matrix Injury in the Glomeruli and Tubulointerstitium of Kidney Allografts with Early Antibody-Mediated Rejection
Antibody-mediated rejection (AMR) accounts for >50% of kidney allograft losses. AMR is caused by donor-specific antibodies (DSA) against HLA and non-HLA antigens in the glomeruli and the tubulointerstitium, which together with high interferon gamma (IFNɣ) and tumor necrosis factor-alpha (TNFα), trig...
ORGANISM(S): Homo sapiens (Human) 
2020-09-22 | PXD017580 | Pride
Glomeruli Basement membrane Glomerular microvascular endothelial cells Tubulointerstitium Systems biology Hla class-i Antibody-mediated rejection Biopsy Kidney Cathepsins. Laser-capture microdissection Proximal tubular epithelial cells Laminin Galectin-1 Glutathione s-transferase omega-1 Extracellular matrix Cytokines Remodeling Proteomics 
GenomicsTubulointerstitium RNAseq Voom Transformed Transcriptome from the Neptune Cohort
Tubulointerstitium RNAseq Voom Transformed Transcriptome from the Neptune Cohort
PRJNA907365 | ENA
TranscriptomicsTubulointerstitium RNAseq Voom Transformed Transcriptome from the Neptune Cohort
Tubulointerstitium RNAseq Voom Transformed Transcriptome from the Neptune Cohort
ORGANISM(S): Homo sapiens 
2022-12-09 | GSE219185 | GEO
GenomicsGene expression from microdissected glomeruli and tubulointerstitium of NZM2328 mice
Gene expression from microdissected glomeruli and tubulointerstitium of NZM2328 mice
PRJNA852235 | ENA
UnknownNovel insights into the disease transcriptome of human diabetic glomeruli and tubulointerstitium.
Not available
S-EPMC7716805 | biostudies-literature
UnknownSpatial proteomics to discover aging-associated alterations in the renal tubulointerstitium.
Not available
S-EPMC12509392 | biostudies-literature
TranscriptomicsGene expression from microdissected glomeruli and tubulointerstitium of NZM2328 mice
To characterize molecular profiles through the development of lupus nephritis and identify risk factors for end organ damage, we carried out gene expression analysis of microdissected kidneys from lupus-prone NZM2328 mice. We identified a continuum of inflammatory processes associated with the progr...
ORGANISM(S): Mus musculus 
2023-07-14 | GSE206806 | GEO
Unknown3D Humanized Bioprinted Tubulointerstitium Model to Emulate Renal Fibrosis In Vitro.
Not available
S-EPMC11582511 | biostudies-literature
UnknownAn integrated bioinformatics approach to identify key biomarkers in the tubulointerstitium of patients with focal segmental glomerulosclerosis and construction of mRNA-miRNA-lncRNA/circRNA networks.
Not available
S-EPMC11001368 | biostudies-literature
ProteomicsSpatial proteomics to discover aging-associated alterations in the renal tubulointerstitium
The preservation of tissue architecture and morphology, in formalin-fixed paraffin-embedded (FFPE) tissue enables spatial resolution at the cellular and sub-cellular level. Laser capture microdissection (LCM) combined with liquid chromatography mass spectrometry analysis has enabled the collection o...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD059176 | Pride
Ffpe Lcm Kidney Lc-ms/ms 
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