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TranscriptomicsRNA seq in U-937 cells wildtype clones and rs2431697 region deletion clones
rs2431697 is a SLE risk SNP, genetic and epigenomic analysis indicate that rs2431697-containing region is an enhancer region. To test the function and regulated genes of rs2431697-containing genes, we deleted rs2431697-containing region in U-937 cells, and performed the RNA-seq to detect the gene ex...
ORGANISM(S): Homo sapiens 
2020-11-05 | E-MTAB-8978 | biostudies-arrayexpress
TranscriptomicsExpression data from U-937 cells exposed to nanosecond duration electrical pulses
It is unclear how nanosecond electrical pulses affect gene expression. We used microarrays to identify how cells respond to this specific type of stress U-937 cells were exposed to 100, 10 nanosecond duration pulses at 150 kV/cm. Gene expression was analyzed 4 hrs post exposure
ORGANISM(S): Homo sapiens 
2016-02-16 | E-GEOD-77908 | biostudies-arrayexpress
TranscriptomicsDeregulation of genes in SH-SY5Y treated with supernatant from U-937-HIV-1 infected cells
It is well known that HIV-1 does not infect neurons, however neurons are the most affected cells by the virus. Several studies linked the deregulation of neuronal transcriptional machinery to single HIV proteins, however the impact of the all the viral proteins on neurons remain unknown. In here we ...
ORGANISM(S): Homo sapiens 
2012-12-07 | E-GEOD-42615 | biostudies-arrayexpress
TranscriptomicsRNA-seq data of rs2280381-containing region knock out clone in U-937 cell line
rs2280381 is an autoimmune disease susceptible variant, which has been reported to be associated with SLE, RA and SSc. Genetic and epigenomic analysis indicate that the rs2280381-containing region is an enhancer region in monocyte. To test the function and regulated genes of the rs228381-containing ...
ORGANISM(S): Homo sapiens 
2022-02-25 | E-MTAB-11306 | biostudies-arrayexpress
GenomicsExpression Data from DMSO or honokiol treated THP-1 and U-937 cells
Expression Data from DMSO or honokiol treated THP-1 and U-937 cells
PRJNA822937 | ENA
GenomicsAnalysis of chromosomal structual aberratons in U-937 cell line
Analysis of chromosomal structual aberratons in U-937 cell line
PRJNA1282710 | ENA
GenomicsEffect of depletion of FOXO3A on gene expression of U-937 cells
Effect of depletion of FOXO3A on gene expression of U-937 cells
PRJNA903103 | ENA
GenomicsRNA seq in U-937 cells wildtype clones and rs2431697 region deletion clones
RNA seq in U-937 cells wildtype clones and rs2431697 region deletion clones
PRJEB37944 | ENA
TranscriptomicsRNA-seq of rs2280381-containing region knock out clone in U937
rs2280381 is an autoimmune disease susceptible loci, which have be reported to be associated with SLE, RA and SSc.Genetic and epigenomic analysis indicate that rs2280381-containing region is an enhancer region in monocyte. To test the function and regulated genes of rs228381-containing region, we de...
ORGANISM(S): Homo sapiens 
2021-07-01 | E-MTAB-10126 | biostudies-arrayexpress
ProteomicsIdentify the binding protein of a 41-bp DNA sequence harboring rs2431697
we performed DNA-affinity precipitation assay (DAPA) followed by mass spectrometry to identify the possible candidates that specifically bind to the 41-bp nucleotide sequence containing rs2431697 using U-937 cell nuclear extracts.
ORGANISM(S): Homo sapiens (Human) 
2020-12-14 | PXD021334 | Pride
Lc-ms U-937 Rs2431697 Dapa 
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