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ProteomicsThe N-terminal region of DNMT3A combines multiple chromatin reading motifs to guide recruitment
DNA methyltransferase 3A (DNMT3A) plays a critical role in establishing and maintaining DNA methylation patterns. However, the mechanisms underlying DNMT3A recruitment to and function within different chromatin environments remain unclear. Using a combination of biochemical and structural approaches...
ORGANISM(S): Homo sapiens (Human) 
2024-10-16 | PXD056554 | Pride
Dnmt3a Udr Histone modifications Nucleosomes Chromatin 
ProteomicsMultiomics Analyses of Vesicular Transport Pathway-Specific Transcripts and Proteins in Ovine Amnion: Responses to Altered Intramembranous Transport
Amniotic fluid volume (AFV) is determined primarily by the rate of intramembranous (IM) transport of AF cross the amnion. Intramembranous transport is characterized as vesicular endocytotic and transcytotic processes regulated by fetal urine-derived stimulators and AF inhibitors. Our objectives were...
ORGANISM(S): Ovis aries 
2021-07-21 | PXD013135 | Pride
Amniotic fluid volume Intramembranous absorption Isobaric labeling Proteomics Vesicular transport Internal reference scaling Transcriptomics 
UnknownHow Commonly Is the Diagnosis of Gastric Low Grade Dysplasia Upgraded following Endoscopic Resection? A Meta-Analysis.
Not available
S-EPMC4504521 | biostudies-literature
UnknownRelationship of adiposity to bone volumetric density and microstructure in men and women across the adult lifespan.
Not available
S-EPMC3650114 | biostudies-literature
UnknownRevisiting the Trans-Ancestry Genetic Correlation of Refractive Error.
Not available
S-EPMC12395803 | biostudies-literature
UnknownAcetylation of 53BP1 dictates the DNA double strand break repair pathway.
Not available
S-EPMC5778472 | biostudies-literature
UnknownCharacterization of Resistance in Gram-Negative Urinary Isolates Using Existing and Novel Indicators of Clinical Relevance: A 10-Year Data Analysis.
Not available
S-EPMC7175163 | biostudies-literature
UnknownExosomal microRNA Panels for Detecting Early-Stage Non-Small Cell Lung Cancer.
Not available
S-EPMC12608640 | biostudies-literature
UnknownDephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks.
Not available
S-EPMC4030556 | biostudies-literature
UnknownStructural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction.
Not available
S-EPMC11266573 | biostudies-literature
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