Sort   by:  
 Page size 
ProteomicsCapillary electrophoresis coupled to electrospray ionization tandem mass spectrometry (CE-MS/MS) for ultra-sensitive proteomic analysis of limited sample
In this work, we developed an ultra-sensitive CE-MS/MS method for bottom-up proteomics analysis of limited samples, down to sub-nanogram levels of total protein. Analysis of 880 pg and 88 pg of HeLa protein digest standard by CE-MS/MS yielded ~1,100±46 and ~160±59 proteins, respectively, demonstrati...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027226 | Pride
Ultra-low flow liquid phase separation Ce-ms Ultra-sensitive proteomics Monolithic columns Capillary electrophoresis Rp-nlc-ms 
ProteomicsSystematic Workflow Optimization for Ultra-Sensitive Targeted Immunopeptidomics
Epitope detection sensitivity remains a primary bottleneck in mass spectrometry (MS)-based immunopeptidomics, as conventional discovery-based workflows such as data-dependent (DDA) and data-independent acquisition (DIA) frequently lack the sensitivity required to detect ultra-low abundant targets. W...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD074199 | Pride
Targeted Immunopeptidomics Hpv Prm Cancer 
ProteomicsSystematic Workflow Optimization for Ultra-Sensitive Targeted Immunopeptidomics
Epitope detection sensitivity remains a primary bottleneck in mass spectrometry (MS)-based immunopeptidomics, as conventional discovery-based workflows such as data-dependent (DDA) and data-independent acquisition (DIA) frequently lack the sensitivity required to detect ultra-low abundant targets. W...
ORGANISM(S): Homo Sapiens Human Papillomavirus 16 
2026-08-27 | PXD074373 | panorama
ProteomicsUltra-sensitive cohort data analysis for Orbitrap Astral based single-cell proteomics
Orbitrap Astral mass spectrometry driven data-independent acquisition (DIA) strategy enables deep profiling in shotgun proteomics and is increasingly adopted in single-cell proteomics (SCP). However, the high proportion of missing values reported by existing DIA software remains a bottleneck for sen...
ORGANISM(S): Homo Sapiens Saccharomyces Cerevisiae 
PXD077556 |
ProteomicsChaFRAtip - Simple, scalable and ultra-sensitive tip-based identification of protease substrates
Temporal profiling of proteolytic cleavage during apoptosis.
ORGANISM(S): Homo sapiens (Human) 
2018-01-24 | PXD006594 | Pride
N-terminomics 
ProteomicsChaFRAtip - Simple, scalable and ultra-sensitive tip-based identification of protease substrates
Enrichment of N-terminal peptides using HPLC-based ChaFRADIC and the novel tip-based ChaFRAtip method.
ORGANISM(S): Homo sapiens (Human) 
2018-01-24 | PXD006595 | Pride
N-terminomics 
UnknownCapillary Electrophoresis Coupled to Electrospray Ionization Tandem Mass Spectrometry for Ultra-Sensitive Proteomic Analysis of Limited Samples.
Not available
S-EPMC8770592 | biostudies-literature
UnknownSpatial characterization and stratification of colorectal adenomas by deep visual proteomics.
Not available
S-EPMC11381895 | biostudies-literature
UnknownMS-EmpiRe Utilizes Peptide-level Noise Distributions for Ultra-sensitive Detection of Differentially Expressed Proteins.
Not available
S-EPMC6731086 | biostudies-literature
ProteomicsSpatial characterization and stratification of colorectal adenomas by Deep Visual Proteomics
Background and Aims: Colorectal adenomas (CRAs) are precursor lesions that can progress to adenocarcinomas. Current clinical guidelines categorize patients into risk groups based on adenoma characteristics observed during index colonoscopy, but this may lead to overtreatment. Our aim was to establis...
ORGANISM(S): Homo sapiens (Human) 
2024-08-04 | PXD046999 | Pride
Spatial Mass spectrometry Pathology Cancer Colorectal adenoma Proteomics Dvp 
Sort   by:  
 Page size