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TranscriptomicsGene expression after 24h Urolithin A incubation in LNCaP cells
The identification of new agents that may modulate the progression of cancer cell growth is of great interest. In this regard, dietary agents can be utilized to identify molecular targets to be used as part of a chemopreventive strategy. Walnuts contain several bioactive compounds, including peduncu...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-65527 | biostudies-arrayexpress
MetabolomicsUrolithin A (UroA) acts at CYP1A1/1B1 substrates leading to enhanced aryl hydrocarbon receptor (AHR) activity in vivo
Not available
ORGANISM(S): Mus musculus 
ST002481 | MetabolomicsWorkbench
ProteomicsUntargeted proteomics of Enterocloster asparagiformis, E. citroniae, E. pacaense treated with DMSO or urolithin M6
Urolithins are a class of bioactive metabolites derived from the metabolism of dietary ellagitannins by the human gut microbiota. In the gut, urolithins are dehydroxylated regioselectively based on microbiota composition and activity. A single 9-hydroxy urolithin dehydroxylase (ucd) operon in gut re...
ORGANISM(S): Enterocloster hominis (ex Hitch et al. 2024) Enterocloster citroniae Enterocloster asparagiformis Bacteria 
2025-11-12 | PXD066865 | Pride
Microbiome Dmso M6 Bacteria Enterocloster Urolithin 
ProteomicsUntargeted proteomics on Enterocloster bolteae DSM 15670 Treated with urolithin C
Urolithin A is a polyphenol derived from the multi-step metabolism of dietary ellagitannins by the human gut microbiota which can affect host health. Most, but not all, individuals harbor a microbiota capable of urolithin A production; however, the enzymes that dehydroxylate its dietary precursor, u...
ORGANISM(S): Enterocloster bolteae ATCC BAA-613 Bacteria 
2024-12-16 | PXD048514 | Pride
Metabolism Proteomics Bacteria Enterocloster bolteae Dsm 15670 Urolithin a Molybdopterin Urolithin c Untargeted Oxidoreductase Urolithin 
GenomicsDetermining effects of microbial metabolite, Urolithin A on colon epithelial cells
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells
PRJNA453152 | ENA
GenomicsEffect of Urolithin A on T cell differentiation and gene expression
Effect of Urolithin A on T cell differentiation and gene expression
PRJNA881344 | ENA
ProteomicsCombination Therapy with Nisin, Urolithin B, and Vincristine Exhibits Synergistic Antiproliferative and Pro-Apoptotic Effects Against Human Lymphoma Cells: Evidence From Proteomics
This study investigates the synergistic antitumor efficacy of a triple combination therapy—Nisin (N), Urolithin B (UB), and Vincristine (Vinc)—against human HBK11 lymphoma cells, with an emphasis on proteomic mechanisms of action. The findings elucidate the molecular underpinnings of this novel comb...
ORGANISM(S): Homo sapiens (Human) 
2025-09-19 | PXD065631 | Pride
Vincristine Urolithin b Synergy Apoptosis Nisin Proteomics Lymphoma 
GenomicsUrolithin A is a potent modulator of cGAS-Sting signaling pathway
Urolithin A is a potent modulator of cGAS-Sting signaling pathway
PRJNA930416 | ENA
GenomicsUrolithin A mitigates behavioral and synaptic deficits associated with epilepsy through VDAC-1 inhibition: A novel treatment approach
Urolithin A mitigates behavioral and synaptic deficits associated with epilepsy through VDAC-1 inhibition: A novel treatment approach
PRJNA1098067 | ENA
GenomicsUrolithin A maintains primordial follicle dormancy and prevents cyclophosphamide-induced follicle loss by inhibiting the PI3K/Akt signaling
Urolithin A maintains primordial follicle dormancy and prevents cyclophosphamide-induced follicle loss by inhibiting the PI3K/Akt signaling
PRJNA1276330 | ENA
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