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DNA damage caused by UV radiation initiates cellular recovery mechanisms, which involve activation of DNA damage response pathways, cell cycle arrest and apoptosis. To assess cellular transcriptional responses to UVC-induced DNA damage we compared time course responses of human skin fibroblasts to l...
ORGANISM(S): Homo sapiens 
This proteomics study analyzed E. coli samples from different treatment groups (UVC alone and sequential UVA - UVC with nitrite) to explore how the combined treatment suppresses bacterial repair mechanisms.
ORGANISM(S): Escherichia Coli 
2026-01-30 | PXD073828 |
Drynaria roosii raw sequence reads of different UVC treatments
Ultraviolet C (UVC) light has long been used as a sterilizing agent, primarily through devices that emit at 254 nm. Depending on the dose and duration of exposure, UV 254 nm can cause erythema and photokeratitis and potentially cause skin cancer since it directly modifies nitrogenated nucleic acid b...
ORGANISM(S): Homo sapiens (Human) 
2026-02-05 | PXD037726 | Pride
Ultraviolet C radiation (UVC) damages the nuclear and mitochondrial genomes; this damage is repaired in the nuclear but not mitochondrial genome. Ethidium bromide (EtBr) inhibits mitochondrial DNA replication. We were interested in the transcriptomic response to exposure to UVC, EtBr, and the combin...
ORGANISM(S): Caenorhabditis elegans 
Time-course RNA-Seq analysis of UVC exposed Ramazzottius varieornatus.
Time-course RNA-Seq analysis of Ramazzottius varieornatus exposed to UVC for up to 72 hours
ORGANISM(S): Ramazzottius varieornatus 
2022-03-25 | GSE152753 | GEO
It is widely acknowledged that gasdermin family proteins, which are known as the executors of pyroptosis, undergo protease-mediated cleavage prior to inducing pyroptosis. Here, we unexpectedly discovered a non-canonical form of pyroptosis mediated by full-length GSDME (FL-GSDME) without any proteoly...
ORGANISM(S): Homo sapiens (Human) 
2024-06-17 | PXD051840 | Pride
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