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ProteomicsA novel Golgi-associated Vangl2 Translational variant is required for PCP regulation in vertebrates
First described in Drosophila melanogaster, planar cell polarity (PCP) is a developmental process essential for embryogenesis and development of polarized structures in Metazoans. This signaling pathway involves a set of evolutionarily conserved genes encoding transmembrane (Vangl, Frizzled, Celsr) ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2024-04-09 | PXD021794 | Pride
Lc-msms Pcp Vangl2 Xenopus 
GenomicsNuclear VANGL2 inhibits mammary differentiation [CUT&RUN]
Nuclear VANGL2 inhibits mammary differentiation [CUT&RUN]
PRJNA1067137 | ENA
GenomicsNuclear VANGL2 inhibits mammary differentiation [RNA-seq]
Nuclear VANGL2 inhibits mammary differentiation [RNA-seq]
PRJNA1067138 | ENA
GenomicsNuclear VANGL2 inhibits mammary differentiation
Nuclear VANGL2 inhibits mammary differentiation
PRJNA1067140 | ENA
TranscriptomicsNuclear VANGL2 inhibits mammary differentiation [RNA-seq]
Planar cell polarity PCP proteins coordinate tissue morphogenesis by governing cell patterning and polarity. Asymmetrically localized on the plasma membrane of cells, transmembrane PCP proteins aretrafficked by endocytosis, suggesting they may have intracellular functions that are dependent or indep...
ORGANISM(S): Mus musculus 
2024-01-30 | GSE253794 | GEO
GenomicsNuclear VANGL2 inhibits mammary differentiation [CUT&RUN]
Planar cell polarity PCP proteins coordinate tissue morphogenesis by governing cell patterning and polarity. Asymmetrically localized on the plasma membrane of cells, transmembrane PCP proteins aretrafficked by endocytosis, suggesting they may have intracellular functions that are dependent or indep...
ORGANISM(S): Mus musculus 
2024-01-30 | GSE253793 | GEO
UnknownFunctional analysis of germline VANGL2 variants using rescue assays of vangl2 knockout zebrafish.
Not available
S-EPMC10772043 | biostudies-literature
UnknownNuclear VANGL2 Inhibits Lactogenic Differentiation.
Not available
S-EPMC10854645 | biostudies-literature
UnknownVangl2 regulates E-cadherin in epithelial cells.
Not available
S-EPMC4221783 | biostudies-literature
UnknownMolecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes.
Not available
S-EPMC3460870 | biostudies-literature
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