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ProteomicsDisassembly of Functional Membrane Microdomains Relapses Antibiotic Resistance in Staphylococcus aureus
Bacteria spatially confine cellular processes like protease secretion and signal transduction in membrane platforms termed functional membrane microdomains, which in certain organisational and functional features resemble the lipid rafts of eukaryotic cells. However, a rigorous understanding of thei...
ORGANISM(S): Staphylococcus aureus 
2019-01-08 | PXD006546 | Pride
Drm Dsm Membrane platforms Staphylococcus aureus Lc-ms/ms 
ProteomicsThe 3’-UTR of MYC couples RNA polymerase II function to ribonucleotide levels
Deregulated expression of MYC enhances glutamine utilization and renders cell survival dependent on glutamine, inducing “glutamine addiction”. Surprisingly, colon cancer cells that express high levels of MYC due to WNT pathway mutations, are not glutamine-addicted but undergo a reversible cell cycle...
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD005829 | Pride
Myc Mrna-protein interaction Glutamine Nanolc-ms/ms 
ProteomicsA census of RNA/protein complexes in a model Gram-positive bacterium reveals exonuclease-mediated sRNA activation in competence regulation
22 total proteome samples from S. pneumoniae wild type resolved on a glycerol gradient resulting in 20 fractions and a pellet fraction. A lysate sample is given as input control.
ORGANISM(S): Streptococcus pneumoniae TIGR4 
2020-04-08 | PXD015835 | Pride
Streptoccocus pneumoniae Grad-seq Yham Cbf1 
ProteomicsA census of RNA/protein complexes in a model Gram-positive bacterium reveals exonuclease-mediated sRNA activation in competence regulation
Affinity purification samples performed with different sRNAs as the bait. Single lanes were cut from a gel and submitted for MS.
ORGANISM(S): Streptococcus pneumoniae TIGR4 
2020-04-08 | PXD015842 | Pride
Cbf1 Streptococcus pneumoniae Grad-seq Csrna 
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