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While blood transcriptional profiling has improved diagnosis and understanding of disease pathogenesis of adult tuberculosis (TB), no studies applying gene expression profiling of children with TB have been described so far. In this study, we have compared whole blood gene expression in childhood TB...
ORGANISM(S): Homo sapiens 
Megakaryoblastic leukemia 1 (MKL1) promotes the regulation of essential cell processes, including actin cytoskeletal dynamics by co-activating serum response factor. Recently, the first human case with MKL1 deficiency has been identified, leading to a novel primary immunodeficiency. We report a seco...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD014633 | Pride
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