Virion assembly

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Tow Center for Developmental Oncology, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Departments of Pediatrics, Pharmacology, and Physiology & Biophysics, Weill Cornell Medical College, Cornell University, New York, NY, USA. (1)
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The host exosome biogenesis pathway is essential for human cytomegalovirus virion assembly and egress

Human Cytomegalovirus (HCMV) infects over 50% of humans, is a leading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals. To expand the molecular knowledge governing virion assembly and egress, we initiated a proteomics-based investigation and identified a ...

ORGANISM(S): Homo sapiens (Human) Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)

2021-02-22 | PXD015081 | Pride

Mass spectrometry-based characterization of the virion proteome and phosphoproteome of human cytomegalovirus

The assembly of human cytomegalovirus (HCMV) virions is an orchestrated process that requires, as an essential prerequisite, the complex crosstalk between viral structural proteins. So far, however, the mechanisms governing the successive steps in the constitution of virion protein complexes remaine...

ORGANISM(S): Homo sapiens (Human) Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)

2020-06-05 | PXD012921 | Pride

Human cytomegalovirus virion composition proteins phosphorylation mass spectrometry-based proteomics

Structure and Assembly of TP901-1 Virion Unveiled by Mutagenesis.

Not available

S-EPMC4493119 | biostudies-literature

Anti-phage defence through inhibition of virion assembly.

Not available

S-EPMC10884400 | biostudies-literature

Using a Virion Assembly-Defective Dengue Virus as a Vaccine Approach.

Not available

S-EPMC6189489 | biostudies-literature