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Virus-host protein-protein interactions (PPIs) are fundamental to viral infections, yet high-resolution identification within the native context of intact infected cells has remained an unsolved challenge. Here, we developed structural host-virus interactome profiling (SHVIP) that combines in situ c...
ORGANISM(S): Homo sapiens (Human) Human alphaherpesvirus 1 
2025-06-13 | PXD047422 | Pride
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoproteomic and...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD036077 | Pride
The Zika virus (ZIKV) is a mosquito-borne Flavivirus and can be transmitted through an infected mosquito bite or through human-to-human interaction by sexual activity, blood transfusion, breastfeeding or perinatal exposure. After the 2015-2016 outbreak in Brazil, a strong link between ZIKV infection...
ORGANISM(S): Homo sapiens (Human) 
2020-06-18 | PXD014961 | Pride
African swine fever virus (ASFV) is a large DNA virus causing a highly contagious disease in domestic and wild boar, for which no treatment is available. ASFV vaccine development is hindered by large gaps in knowledge considering virus protein function and virus-host interaction. This study shows th...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-01-23 | PXD035695 | Pride
African swine fever virus (ASFV) is a large DNA virus causing a highly contagious disease in domestic and wild boar, for which no treatment is available. ASFV vaccine development is hindered by large gaps in knowledge considering virus protein function and virus-host interaction. This study identifi...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2025-07-23 | PXD047794 | Pride
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