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We present here the first study evaluating the dynamic proteome changes in the remodeling process of decellularized tissue by reseeded cells using vocal fold mucosa as the model system.
ORGANISM(S): Homo sapiens (Human) 
2016-01-06 | PXD002734 | Pride
This dataset brief is about the descriptive proteomic comparison of human oral mucosa and vocal fold tissues by high-resolution mass spectrometry (CID-MS/MS). The vast majority of voice disorders is associated with changes of the unique but delicate tissue of the human vocal folds, wheras the abili...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD025519 | Pride
We used microarrays to characterize transcriptome profiles of rat vocal fold tissue following surgical injury (vs. naive tissue); rat vocal fold fibroblasts harvested from scar tissue at the 60 d time point (vs. naive fibroblasts); rat vocal fold scar fibroblasts treated with siRNA against the coll...
ORGANISM(S): Rattus norvegicus 
Expression data from rat vocal fold at different periods after vocal fold injury
Injuries of the vocal folds frequently heal with scar formation, which can have lifelong detrimental impact on voice quality. Current treatments to prevent or resolve scars of the vocal fold mucosa are highly unsatisfactory. In contrast, the adjacent oral mucosa is mostly resistant to scarring. Thes...
ORGANISM(S): Ovis aries 
2017-01-23 | PXD005106 | Pride
Expression data from rat vocal fold at different periods after vocal fold injury (miRNA)
Injection of Vocal Fold Lamina Propria-Derived Hydrogels Modulates Fibrosis in Injured Vocal Folds
Decellularized extracellular matrix (dECM) is used to make regenerative biomaterials. As the ECM markups vary across organs, derived dECM products may possess different molecular and biological profiles as well. This study aims to compare the proteomic profiles of dECM biomaterials derived from sma...
ORGANISM(S): Sus scrofa (Pig) 
2023-02-01 | PXD033621 | Pride
We used microarrays to characterize transcriptome profiles of rat vocal fold tissue following surgical injury (vs. naive tissue); rat vocal fold fibroblasts harvested from scar tissue at the 60 d time point (vs. naive fibroblasts); rat vocal fold scar fibroblasts treated with siRNA against the colla...
ORGANISM(S): Rattus norvegicus 
2014-10-09 | GSE62204 | GEO
The objective of this study was to obtain a comprehensive proteome of euhydrated and systemically dehydrated rabbit vocal folds. We hypothesized that a mild-moderate systemic dehydration level would lead to changes in protein levels. New Zealand White rabbits were randomly assigned to euhydrated (c...
ORGANISM(S): Oryctolagus Cuniculus 
2020-12-17 | MSV000086612 | MassIVE
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