Sort   by:  
 Page size 
ProteomicsProteomic signatures of the serological response to flu vaccination in a large human cohort study
This project investigates the serum proteomic signatures of the serological response to flu vaccination. We profiled the serum proteome of 160 flu vaccine recipients from a cohort study conducted in 2019-2020 season, with DIA-MS based proteomics. We compared the protein level between low and high re...
ORGANISM(S): Homo sapiens (Human) 
2022-11-17 | PXD036718 | Pride
Human cohort Serum proteomics Flu vaccination 
ProteomicsTime series and steady state proteomics of Pseudomonas aeruginosa phenazine mutants
Microbes in biofilms face the challenge of substrate limitation. In particular, cells in Pseudomonas aeruginosa biofilms growing in the laboratory or during host colonization often become limited for oxygen. Previously we found that phenazines, antibiotics produced by P. aeruginosa, balance the intr...
ORGANISM(S): Pseudomonas aeruginosa PA14-RN6 
2018-10-19 | PXD008924 | Pride
Biofilm  phenazines  denitrification  pseudomonas aeruginosa 
ProteomicsMeiotic DNA breaks activate a streamlined response that largely avoids protein level changes-DDA
To understand the proteome and phosphoproteome level responses to meiotic DNA breaks, we have compared protein phosphorylation and protein levels in cells spo11-YF (cannot form meiotic DNA breaks) cells to SPO11 (can form meiotic breaks) cells.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-15 | PXD031779 | Pride
Spo11 Dna damage Meiosis Yeast 
ProteomicsHigh-resolution proteomics of Zika and Dengue serum samples
We used data independent acquisition (DIA) mass spectrometry (MS) to profile ~800 proteinsfrom 122 serum samples Dengue or Zika Trinidadian patients. Two time points were collectedper patient. The DIA MS data were matched against a spectral library generated from high pH/low pH separated pooled seru...
ORGANISM(S): Homo sapiens (Human) 
2021-03-09 | PXD015422 | Pride
Dia Serum Dengue Zika 
ProteomicsTranscriptome and proteome profiling of motor neuron model subjected to protein misfolding stress
To identify molecular differences between closely related motor neurons relevant for understanding of neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS), we exploited induced cranial and spinal motor neuron populations from mouse embryonic stem cells. We performed a large scale ...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-06 | PXD018070 | Pride
Motor neuron Als Stem cells Proteomics 
ProteomicsHuman hnRNP H1 knockdown proteomics
HNRNP1 was characterized in a multi-dimensional study involving RNAi knockdown of the protein in HeLa cells. Label-free proteomics was used to characterize protein expression changes.
ORGANISM(S): Homo sapiens (Human) 
2016-01-25 | PXD000895 | Pride
Human Hnrnph1 
ProteomicsMammalian proteome changes during oxidative stress and stress of the endoplasmic reticulum
Stress due to protein misfolding in the endoplasmic reticulum affects transcription and translation, RNA and protein degradation. By integrating several large-scale datasets, we quantified transcription, translation, RNA-protein binding events, and protein levels for several thousands of genes in He...
ORGANISM(S): Homo sapiens (Human) 
2018-10-11 | PXD008575 | Pride
Er stress Translation Proteomics Oxidative stress 
ProteomicsK63 polyubiquitination is a new modulator of the oxidative stress response, SRM data
Ubiquitination is a post-translational modification that signals multiple processes, including protein degradation, trafficking and DNA repair. Polyubiquitin accumulates globally during the oxidative stress response, and this has been mainly attributed to increased ubiquitin conjugation and perturba...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-01-26 | PXD000979 | Pride
Q-exactive Yeast Silac Lc-ms/ms 
ProteomicsK63 polyubiquitination is a new modulator of the oxidative stress response, shotgun data
Ubiquitination is a post-translational modification that signals multiple processes, including protein degradation, trafficking and DNA repair. Polyubiquitin accumulates globally during the oxidative stress response, and this has been mainly attributed to increased ubiquitin conjugation and perturba...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-01-26 | PXD000960 | Pride
K63 ubiquitination yeast oxidative stress 
ProteomicsSex-specific glycosylation of secreted immunomodulatory proteins in the filarial nematode Brugia malayi
The extended persistence of filarial nematodes within a host suggests immunomodulatory mechanisms that allow the parasites to resist or evade the host immune response. There is increasing evidence for immunomodulatory glycans expressed by a diversity of parasitic worms. In this study, we integrate m...
ORGANISM(S): Brugia malayi 
2026-09-15 | PXD024252 | Pride
Glycosylation Glycoproteins Brugia malayi Immunomodulation Secretome 
Sort   by:  
 Page size