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ProteomicsN-terminal modification of eGFP by LC-MSMS
We used an in-depth analysis of the characteristics of eGFP as a proof-of-principle analyte to establish a robust assay for the determination of degradation rates on the single-cell level using microinjection and live-cell microscopy. We aimed to determine the influence of the exposed n-terminal ami...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2025-05-06 | PXD042569 | Pride
Lc-msms N-degron Ptm Egfp Acetylation 
UnknownUGT1A1 (TA)n Promoter Genotype: Diagnostic and Population Pharmacogenetic Marker in Serbia.
Not available
S-EPMC6231317 | biostudies-literature
UnknownEGFR Polymorphism and Survival of NSCLC Patients Treated with TKIs: A Systematic Review and Meta-Analysis.
Not available
S-EPMC7104312 | biostudies-literature
TranscriptomicsRNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury
We assessed the roles of repopulating microglia in brain repair using mouse models. In this project, we show that removal of microglia from the mouse brain has little impact on the outcome of TBI but inducing the turnover of these cells through either pharmacologic or genetic approaches can yield a ...
ORGANISM(S): Mus musculus 
2020-02-15 | E-MTAB-8765 | biostudies-arrayexpress
ProteomicsUbiquitination site analysis of eGFP by DARPin-based bioPROTACs analysed by LC-MS-MS
We investigated design principles of DARPin-based bioPROTACs targeting the model substrate GS-eGFP (eGFP with an n-terminal tag, necessary for proteasomal unfolding). Using a highly active E3 ligase domain from CHIP and nine well-characterized DARPins, we evaluated their ability to induce proteasoma...
ORGANISM(S): Homo sapiens (Human) 
2025-06-05 | PXD063877 | Pride
Ubiquitination Darpin Bioprotac Egfp 
TranscriptomicsMicroarray data from YTHDF2-deficient pre-leukemic cells and control pre-leukemic cells
YTHDF2 is overexpressed in a broad spectrum of human acute myeloid leukemias (AML). To study the role of YTHDF2 in leukemia, c-Kit+ cells from foetal livers of Ythdf2fl/fl;Vav-iCre (Ythdf2CKO) and Ythdf2fl/fl (Ythdf2CTL) 14.5 dpc embryos were transduced with Meis1 and Hoxa9 oncogenes and serially re...
ORGANISM(S): Mus musculus 
2019-04-05 | E-MTAB-6783 | biostudies-arrayexpress
UnknownGenetic Characterization of Short Stature Patients With Overlapping Features of Growth Hormone Insensitivity Syndromes.
Not available
S-EPMC8530715 | biostudies-literature
UnknownThe nature of π-hole interactions between iodide anions and quinoid rings in the crystalline state.
Not available
S-EPMC9980391 | biostudies-literature
UnknownEnvironmental Gradients Shaping the Freshwater Bryophyte Communities of Croatia (Western Balkans).
Not available
S-EPMC9230072 | biostudies-literature
UnknownEcological Preferences and Indication Potential of Freshwater Bryophytes-Insights from Croatian Watercourses.
Not available
S-EPMC9788454 | biostudies-literature
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