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ProteomicsAn Insight into Glyco-microheterogeneity of Plasma von Willebrand Factor (vWF) by Mass Spectrometry
Von Willebrand Factor (vWF), a plasma glycoprotein, plays essential roles in primary hemostasis, in cooperation with other coagulation factors. The glycosylation affects many biological phases during the protein life-cycle. In this work, we comprehensively characterized the microheterogeneity at all...
ORGANISM(S): Homo sapiens (Human) 
2022-02-23 | PXD006567 | Pride
Glycosylation Cid Microheterogeneit Plasma von willebrand factore N-glycan Vwf Mass spectrometry Hcd O-glycan Occupancy 
GenomicsNext Generation Sequencing to analyse regulators of constitutive VWF secretion
Next Generation Sequencing to analyse regulators of constitutive VWF secretion
PRJNA637494 | ENA
GenomicsEpigenetic profiles of young vs old Vwf+ HSCs at single cell level
Epigenetic profiles of young vs old Vwf+ HSCs at single cell level
PRJNA907024 | ENA
TranscriptomicsNext Generation Sequencing to analyse regulators of constitutive VWF secretion
Constitutive VWF secretion can be increased by a range of factors; changes in VWF expression, levels of TNF-alpha or other environmental cues. An RNAseq analysis revealed that expression of RGS4 (Regulator of G protein signalling 4) was reduced in endothelial cells (HUVECs) grown under these conditi...
ORGANISM(S): Homo sapiens 
2020-06-06 | GSE151854 | GEO
GenomicsHeavy Menstrual Bleeding in Adolescents with Low VWF
Heavy Menstrual Bleeding in Adolescents with Low VWF
PRJEB49705 | ENA
TranscriptomicsEffect of von Willebrand factor on gene expression in HUVECs
Von Willebrand factor is a paracrine/autocrine regulator of human mesenchymal stem cell adhesion to distressed/apoptotic endothelial cells. This data set examines effect of vWF on gene expression in HUVECs. HUVECs were maintained in EGM2 media and treated with vWF in Hank's buffered salt solution (...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-19816 | biostudies-arrayexpress
UnknownEnhanced VWF clearance in low VWF pathogenesis: limitations of the VWFpp/VWF:Ag ratio and clinical significance.
Not available
S-EPMC9898599 | biostudies-literature
UnknownEnhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene.
Not available
S-EPMC1895519 | biostudies-literature
ProteomicsCOVID-19 increases extracorporeal coagulation during hemodialysis through upregulation of vWF/FBNL5 signaling
Introduction: COVID-19 has been shown to increase the risk of extracorporeal coagulation during hemodialysis in patients, but the mechanism is unclear. This study aims to investigate the effect and mechanism of COVID-19 on the risk of extracorporeal coagulation during hemodialysis. Methods: A retro...
ORGANISM(S): Homo Sapiens 
PXD044377 |
TranscriptomicsGene profiling of platelet-biased long term hematopoietic stem cells
Gene profiling of LSKCD150+CD48-CD34- hemetopoietic stem cells expressing (Vwf+) or not expressing a Vwf-EGFP BAC transgene
ORGANISM(S): Mus musculus 
2013-08-12 | E-MEXP-3935 | biostudies-arrayexpress
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