Sort   by:  
 Page size 
ProteomicsBinding of Akkermansia muciniphila to mucin is O-glycan specific
The intestinal anaerobic bacterium Akkermansia muciniphila is specialized in the degradation of mucins, which are heavily O-glycosylated proteins that constitute the major components of the mucus lining the intestine. Despite that adhesion to mucins is considered critical for the persistence of A. m...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD051738 | Pride
Akkermansia muciniphila Mucin O-glycan 
ProteomicsC18 nanoLC-MS and Glycogenomics to Facilitate O-Glycan profiling in Human Cells
O-glycosylation is an abundant modification throughout the human proteome and plays a role in, amongst others, regulation of protein cleavage, protein folding, and modulation of cell-cell and -matrix interactions. O-glycosylation type and structure are important for biological function, demanding an...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD029644 | Pride
Keratinocytes Glycogenomics Glycomics Hek293 O-glycan 
ProteomicsRe-analysis of glycoproteomics data with MSFragger-Glyco
Reanalysis of submissions PXD011533 and PXD009476 using MSFragger-Glyco mode. Processed MSFragger results files (pepXML) and PSM tables (psm.tsv) supporting MSFragger-Glyco manuscript (Fast and Comprehensive N- and O-glycoproteomics analysis with MSFragger-Glyco. Recent advances in methods for enric...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-10-06 | PXD021196 | Pride
Glycosylation Glycoproteomics Msfragger Reanalysis O-glycosylation Glycan Glycopeptide N-glycosylation 
GenomicsTruncated O-glycan connection to Cancer: Depletion of O-glycosyltransferase C1GALT1 leads to early PDAC onset and metastasis
Truncated O-glycan connection to Cancer: Depletion of O-glycosyltransferase C1GALT1 leads to early PDAC onset and metastasis
PRJNA413293 | ENA
ProteomicsA Combinatorial Enzymatic Approach for Identifying O-glycopeptides
Proteins glycosylation is primarily characterized as N-glycosylation or O-glycosylation. Recognition of the consensus N-glycosylation sequon (N-X-S/T/C) has enabled the mapping of the glycosite occupancy of intact glycopeptides, whereas O-glycosylation consensus sequons do not exit, making the chara...
ORGANISM(S): Homo sapiens (Human) 
2024-04-25 | PXD042701 | Pride
Rax-based enrichment O-glycosites O-glycosylation Impa Scehcd-based ms/ms 
TranscriptomicsTruncated O-glycan connection to Cancer: Depletion of O-glycosyltransferase C1GALT1 leads to early PDAC onset and metastasis
Aberrant expression of truncated O-glycan structures, such as Tn and STn, is frequently observed in pancreatic ductal adenocarcinoma (PDAC). The focus of our study is to investigate the functional role of truncated O-glycans in PDAC progression and metastasis. Our study revealed that kmockout of C1G...
ORGANISM(S): Homo sapiens 
2018-10-05 | GSE104607 | GEO
ProteomicsBlockage of O-linked glycan biosynthesis in Burkholderia is toxic: Tn7_ogcI_validation
Burkholderia species are associated with several life-threatening human infections, often resulting in high morbidity and mortality rates due to their innate resistance to antibiotics. To improve clinical outcomes, new therapies targeting conserved, yet unique, Burkholderia pathways are needed. One ...
ORGANISM(S): Burkholderia cenocepacia K56-2Valvano 
2025-10-22 | PXD055576 | Pride
Glycosylation Burkholderia 
ProteomicsBlockage of O-linked glycan biosynthesis in Burkholderia is toxic: OgcAB complementation
Burkholderia species are associated with several life-threatening human infections, often resulting in high morbidity and mortality rates due to their innate resistance to antibiotics. To improve clinical outcomes, new therapies targeting conserved, yet unique, Burkholderia pathways are needed. One ...
ORGANISM(S): Burkholderia cenocepacia K56-2Valvano 
2025-10-22 | PXD055163 | Pride
Glycosylation Burkholderia 
ProteomicsBlockage of O-linked glycan biosynthesis in Burkholderia is toxic: OgcA complementation
Burkholderia species are associated with several life-threatening human infections, often resulting in high morbidity and mortality rates due to their innate resistance to antibiotics. To improve clinical outcomes, new therapies targeting conserved, yet unique, Burkholderia pathways are needed. One ...
ORGANISM(S): Burkholderia cenocepacia K56-2Valvano 
2025-10-22 | PXD054956 | Pride
Glycosylation Burkholderia 
ProteomicsBlockage of O-linked glycan biosynthesis in Burkholderia is toxic: OgcI Complementation
Burkholderia species are associated with several life-threatening human infections, often resulting in high morbidity and mortality rates due to their innate resistance to antibiotics. To improve clinical outcomes, new therapies targeting conserved, yet unique, Burkholderia pathways are needed. One ...
ORGANISM(S): Burkholderia cenocepacia K56-2Valvano 
2025-10-22 | PXD054867 | Pride
Glycosylation Burkholderia 
Sort   by:  
 Page size