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MetabolomicsUHPLC-Q-TOF MS-Based Serum Metabolomics Reveals the Therapeutic Effects of Berberine and Wumei Wan on APCmin/+ Mice

APCmin/+ mice (8-week-old) and wild-type C57BL/6 controls were divided into MOD (saline), BBR (100 mg/kg berberine), WMW (17 g/kg Wu Mei Wan), and CON (saline) groups. All mice received daily gavage for 10 weeks under a 60% high-fat diet. Serum samples were collected after euthanasia and subjecte...

2025-10-16 | MTBLS12598 | MetaboLights
UnknownBiosafety and Proteome Profiles of Different Heat Inactivation Methods for Mycobacterium tuberculosis.
Not available
S-EPMC8694153 | biostudies-literature
ProteomicsLC/MS Analysis of Phosphorylated Protein Changes in Mouse Brain Tissue After LPS Treatment and Angong Niuhuang Wan Administration
Introduction: Angong Niuhuang Wan (AGNHW), developed in the Qing dynasty (18th century) for treating consciousness disturbances caused by severe infections, has already been used to treat brain edema caused by ischemia-reperfusion. However, it remains unclear whether AGNHW can ameliorate vascular-or...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD054069 | Pride
Lc/ms Agnhw Phosphoproteome 
ProteomicsMechanism of Zuogui Wan in ameliorating chronic stress-induced intergenerational transmission of ovarian dysfunction via the complement and coagulation cascade pathway
To systematically identify protein targets interacting with traditional Chinese medicine Zuogui Wan, limited proteolysis mass spectrometry (LiP-MS) was employed as a high-throughput screening platform. To investigate the molecular mechanisms underlying chronic unpredictable mild stress (CUMS)-induce...
ORGANISM(S): Rattus Rattus 
PXD063422 |
ProteomicsIP-MS of DCAF1/VprBP interacting proteins in mouse CD4 T cells
DCAF1, also known as VprBP (HIV-1-viral-protein-r-binding-protein), is an evolutionary conserved substrate-binding subunit of CRL4 (Cul4a-Ddb1-Roc1) ubiquitin ligase complex. It is a cellular protein targeted by HIV-1 viral protein R (Vpr). DCAF1 modulates cellular response against HIV in macrophage...
ORGANISM(S): Mus musculus (Mouse) 
2016-01-12 | PXD003180 | Pride
Dcaf1 T cell Vprbp Hiv-1 
TranscriptomicsTranscription profiling of Arabidopsis seedlings to chito-tetramers, chito-octamers and hydrolized chitin
Using the ATH1 Affymetrix microarrays consisting of about 23,000 genes, we examined the response of Arabidopsis seedlings to chito-tetramers, chito-octamers and hydrolyzed chitin after 30 min of treatment.
ORGANISM(S): Arabidopsis thaliana 
2007-07-12 | E-GEOD-2538 | biostudies-arrayexpress
TranscriptomicsComparison of transcriptomes in five varieties of citrus fruit
To identify genes associated with citrus peel development and manifestation of peel disorders, we analyzed flavedo, albedo and juice sac tissues from five types of citrus fruit including, mandarin orange, navel orange, valencia orange, grapefruit and lemon. Fruits of five different citrus cultivars....
ORGANISM(S): Citrus reticulata 
2014-01-01 | E-GEOD-50384 | biostudies-arrayexpress
UnknownEnhancing dyadic outcomes of stroke survivors and caregivers: protocol for a randomised controlled trial.
Not available
S-EPMC12097053 | biostudies-literature
ProteomicsIntegrated multi-omic analysis of Mycobacterium tuberculosis isolates identifies ethionamide resistance-associated gene pair Rv3094c-Rv3095
Global control of the tuberculosis (TB) epidemic is seriously threatened by increasing prevalence of drug resistant (DR) M. tuberculosis (MTB) isolates. Many genome-wide studies have identified DR-associated SNPs and investigated their role in DR mechanisms. However, DR in ~30% of isolates has no cl...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2023-03-10 | PXD017079 | Pride
Transcriptome Mycobacterium tuberculosis Drug resistance Lineage Proteome Baeyer-villiger monooxygenase Phylogenetics Ethionamide Rna-seq 
Proteomicsmice Renal tubular epithelial cells LC-MS/MS
Diabetic nephropathy is considered one of the most common microvascular complications of diabetes and the pathophysiology involves multiple factors. Progressive diabetic nephropathy is believed to be related to the structure and function of the tubular epithelial cells in the kidney. However, the ro...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD029651 | Pride
Mouse Renal tubular epithelial cells Lc-ms/ms 
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