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ProteomicsIdentification of Siglec-E-ligand candidates on BCL-1 mouse B cell line by proximity labeling
Siglec-E is a member of Siglec family of glycan recognition proteins involved in the regulation of myeloid cell activities. Siglec-E preferentially recognizes disialic acid, a glycan epitope consisting of two sialic acids conjugated in alpha2-8 linkage (Zhang JQ et al., Eur J Immunol. 2004, 34:1175...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-25 | PXD013032 | Pride
Lc-msms Siglec-e Mouse Ligand B cell Sialic acid 
UnknownLinked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B.
Not available
S-EPMC4515841 | biostudies-literature
ProteomicsRepression of PRMT5-mediated dimethylation stabilizes vimentin and promotes metastasis in MTAP-loss lung cancer
Abstract The aggressive nature and poor prognosis of lung cancer led us to explore the mechanisms driving disease progression. Utilizing our invasive cell-based model, we identified methylthioadenosine phosphorylase (MTAP) and confirmed its suppressive effects on tumorigenesis and metastasis, and pa...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD031192 | Pride
Human Dimethylation Lung cancer 
TranscriptomicsTranscriptomic profiling of a glioblastoma multiforme patient with matched control brain tissue
To investigate differential gene expression, we analyzed the entire transcriptomes of tumor and matched normal brain tissues obtained from a patient who had glioblastoma multiforme. We extracted and sequenced the mRNA using Illumina GA2 platform. The raw data was analyzed using our recently develop...
ORGANISM(S): Homo sapiens 
2011-10-30 | E-GEOD-33328 | biostudies-arrayexpress
UnknownJoining Illumina paired-end reads for classifying phylogenetic marker sequences.
Not available
S-EPMC7071698 | biostudies-literature
UnknownTranscriptomic profiling of a glioblastoma multiforme patient with matched control brain tissue
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-33328 | biostudies-other
UnknownAssociation of chronic obstructive pulmonary disease with risk of lung cancer in individuals aged 40 years and older: A cross-sectional study based on NHANES 2013-2018.
Not available
S-EPMC11498685 | biostudies-literature
UnknownRNASEQR--a streamlined and accurate RNA-seq sequence analysis program.
Not available
S-EPMC3315322 | biostudies-literature
UnknownSharp Transformation across Morphotropic Phase Boundary in Sub-6 nm Wake-Up-Free Ferroelectric Films by Atomic Layer Technology.
Not available
S-EPMC10646279 | biostudies-literature
ProteomicsIn-situ Click Reaction Coupled with Quantitative Proteomics for Identification of Protein Targets of Catechol Estrogens
Catechol estrogens (CEs) are metabolic electrophiles that actively undergo covalent interaction with cellular proteins, influencing molecular function. There is no feasible method to identify their binders in a living system. Herein, we developed a click chemistry-based approach using ethinylestradi...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-28 | PXD009657 | Pride
Post translational modification Metabolites Proteomics Electrophiles Dimethyl labeling Lc/ms Catechol estrogens Oxidative stress Click chemistry Redox modification 
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