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Over the last two decades, mounting evidence has demonstrated the aberrant expression of miRNAs in different human malignancies, including ovarian carcinomas. In this study, we found that miR-141 were secreted by ovarian cancer cells and transferred to the stromal cells by exosomal pathway. To clari...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026929 | Pride
Molecular Elasticity and Adjustment of Drought Recovery Dynamics of 14N- and 15N-fertilized Legume Medicago truncatula. Climate change in conjunction with population growth necessitates a systems biology approach to characterize plant drought response and a more thorough understanding of the underly...
ORGANISM(S): Medicago truncatula (Barrel medic) (Medicago tribuloides) 
2016-03-29 | PXD001728 | Pride
The distinct phenotypic and prognostic subclasses of human hepatocellular carcinoma (HCC) are difficult to reproduce in animal experiments. Here we have used in vivo gene targeting to insert an enhancer-promoter element at an imprinted chromosome 12 locus in mice, thereby converting ~1 in 20,000 no...
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the following subset Series: GSE35402: miRNA expression profiling of hepatocellular carcinoma induced by AAV in vivo gene targeting at the Rian locus GSE35403: mRNA expression profiling of hepatocellular carcinoma induced by AAV in vivo gene targeting at the Rian locu...
ORGANISM(S): Mus musculus 
The distinct phenotypic and prognostic subclasses of human hepatocellular carcinoma (HCC) are difficult to reproduce in animal experiments. Here we have used in vivo gene targeting to insert an enhancer-promoter element at an imprinted chromosome 12 locus in mice, thereby converting ~1 in 20,000 no...
ORGANISM(S): Mus musculus 
gel_msms
ORGANISM(S): Saccharomyces Cerevisiae 
2002-12-31 | PAe000139 | PeptideAtlas
Human trisomies can alter cellular phenotypes and produce congenital abnormalities such as Down Syndrome (DS). Here we have generated induced pluripotent stem cells (iPSCs) from DS fibroblasts, and introduced a TKNEO transgene into one copy of chromosome 21 by gene targeting. When selecting agains...
ORGANISM(S): Homo sapiens 
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
Here we demonstrate eEF1-alpha and eEF2 stabilisation by M5717 in the intact-cell P. falciparum-infected red blood cells, using thermal Proteome Integral Solubility Alteration (Thermal PISA) assay coupled with Data Independent Acquisition Mass Spectrometry (DIA-MS).
ORGANISM(S): Plasmodium (plasmodium) 
LGG Epilepsy Cohort WGS
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