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UnknownA FEN 1-driven DNA walker-like reaction coupling with magnetic bead-based separation for specific SNP detection.
Not available
S-EPMC10656677 | biostudies-literature
ProteomicsProteomic Profiling Identifies Novel Diagnostic Biomarkers and Molecular subtypes for Mucinous Tubular and Spindle Cell Carcinoma of the Kidney
Mucinous tubular and spindle cell carcinoma (MTSCC) is a relatively rare renal epithelial neoplasm resembling type 1 papillary renal cell carcinoma (PRCC) morphologically and immunohistochemically. The accurate diagnosis of MTSCC remains a challenge. Here, by using proteomic profiling, we characteri...
ORGANISM(S): Homo sapiens (Human) 
2022-02-11 | PXD027972 | Pride
Mucinous tubular and spindle cell carcinoma Immunohistochemistry Proteomic Kidney 
TranscriptomicsGlobal Deterministic and Stochastic Allelic Specific Gene Expression in Single Blastomeres of Mouse Early Embryos
Here we modified a single cell whole transcriptome amplification method to make it capable of amplifying cDNAs as long as 3kb efficiently and unbiasedly. We combined this modified single cell cDNA amplification method with Applied Biosystems next generation sequencing SOLiD™ System to set up a singl...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-22182 | biostudies-arrayexpress
ProteomicsTemporal proteomics of p97/VCP inhibition
To facilitate the development of p97 inhibitors as potential therapeutic agents and help define their clinical application, it is necessary to dissect the mechanism of action (MOA) of p97 inhibitors and compare them with proteasome inhibitors. Moreover, identifying specific cellular markers is criti...
ORGANISM(S): Homo sapiens (Human) 
2021-12-15 | PXD025225 | Pride
Proteasome inhibitor Hct116 P97 inhibitor Proteomic 
TranscriptomicsGene expression profiling of mouse prostate over-expressing the Notch1 intracellular domain.
Molecular signaling that regulates differentiation, survival and proliferation of the prostate luminal epithelial cells has not been thoroughly understood. Herein, we show that increased canonical Notch1 activity suppresses terminal differentiation of prostate luminal epithelial cells but is insuffi...
ORGANISM(S): Mus musculus 
2014-08-07 | E-GEOD-53036 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis wild-type and lwd1lwd2 double mutant to investigate the role of LWD1 and LWD2 in Arabidopsis photoperiod regulation
Transcriptome analysis has revealed a light-regulated WD (tryptophan and aspartate)-containing protein, LWD1. LWD1 and LWD2 share greater than 90% amino acid sequence homology. The lack of phenotype changes in the lwd1 or lwd2 single mutant implies that the proteins function redundantly. The lwd1lwd...
ORGANISM(S): Arabidopsis thaliana 
2008-10-26 | E-GEOD-11762 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis pollen germination and tube growth
Pollen germination, along with pollen tube growth, is an essential process for the reproduction of flowering plants. The germinating pollen with tip-growth characteristics provides an ideal model system for the study of cell growth and morphogenesis. As an essential step towards a detailed underst...
ORGANISM(S): Arabidopsis thaliana 
2008-10-25 | E-GEOD-6696 | biostudies-arrayexpress
UnknownQuantification of an oval optic disc in relation to myopic foveoschisis using swept-source optical coherence tomography.
Not available
S-EPMC8862570 | biostudies-literature
TranscriptomicsTracing the derivation of embryonic stem cells from the inner cell mass by single cell RNA-seq analysis
Here we modified a single cell whole transcriptome amplification method to make it capable of amplifying cDNAs as long as 3kb efficiently and unbiasedly. We combined this modified single cell cDNA amplification method with Applied Biosystems next generation sequencing SOLiD™ System to set up a singl...
ORGANISM(S): Mus musculus 
2013-06-11 | E-GEOD-20187 | biostudies-arrayexpress
UnknownQuality Evaluation of the Root Bark Epidermis of Peony by HPLC-DAD-ESI-MS/MS
Not available
S-EPMC12942668 | biostudies-literature
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