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Microglia, the resident immune cells of the central nervous system (CNS), are critically involved in the pathogenesis of multiple sclerosis (MS). To better understand the molecular changes in these cells during neuroinflammation, we performed high-depth quantitative proteomics on microglia isolated ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-15 | PXD067298 | Pride
In this study, we achieved the quantitative glycoproteomics analysis of a large cohort of clinical specimens including 100 Hepatocellular carcinoma (HCC) and 100 healthy control human serums by using an integrated platform.
ORGANISM(S): Homo Sapiens (human) 
The abnormal induction of macroautophagy/autophagy, a highly conserved lysosome-based degradation pathway, has been postulated as a major toxicity of nanomaterials, whereas little is known on the exact molecular mechanisms. Here, we treated mammalian cells with 16 nm silica nanoparticles (SiNPs), co...
ORGANISM(S): Rattus Norvegicus 
2019-12-01 | PXD012196 |
A Label-free quantitative proteomic profiling was performed on MEFs with or without nutrient starvation.
ORGANISM(S): Mus Musculus 
2022-10-15 | PXD025450 |
144 tissue samples from postmortem lung, liver, kidney, heart, spleen, testis and thyroid collected from 19 COVID-19 cases and 74 control specimens from 56 non-COVID-19 individuals were analyzed by PCT and TMT 16-plex based proteomics.
ORGANISM(S): Homo Sapiens 
2020-12-11 | PXD022775 |
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