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MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
ProteomicsTMT-based quantitative proteomic analysis revealed that FBLN2 and NPR3 are involved in the early MSCs osteogenic differentiation
The intriThe intricate balance between MSCs differentiation to osteoblasts or adipocytes is finely regulated. To explore novel participating molecules, we screened for early-stage osteogenesis- or adipogenesis-based MSCs protein expression profile using TMT-based quantitative proteomic analysis. Pro...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041404 | Pride
Marrow mesenchymal stem cells Differentiation Adipogenesis Human Osteogenesis 
UnknownChanges in surface characteristics and adsorption properties of 2,4,6-trichlorophenol following Fenton-like aging of biochar.
Not available
S-EPMC7900105 | biostudies-literature
UnknownMolecules interacting with CasL-Like 2 enhances tumor angiogenesis and progression by activating mTOR/HIF1α/VEGF pathway in kidney renal clear cell carcinoma.
Not available
S-EPMC12541079 | biostudies-literature
TranscriptomicsThe pattern of gene expression in human CD15+ myeloid progenitor cells
We performed a genome-wide analysis of gene expression in primary human CD151 myeloid progenitor cells. By using the serial analysis of gene expression (SAGE) technique, we obtained quantitative information for the expression of 37,519 unique SAGE-tag sequences. Of these unique tags, (i) 25% were de...
ORGANISM(S): Homo sapiens 
2008-10-03 | E-GEOD-13007 | biostudies-arrayexpress
TranscriptomicsIdentification of genes modulated by JIB-04 in lung cancer cells
JIB-04 is an inhibitor of Jumonji histone demethylases identified through a cell based screen that measures the reactivation of an epigenetically silenced transgene. The active JIB-04 E-isomer shows selectivity for cancer vs. normal cells affecting both transcriptional patterns and cell viability in...
ORGANISM(S): Homo sapiens 
2013-07-08 | E-GEOD-46632 | biostudies-arrayexpress
TranscriptomicsThe pattern of gene expression in human CD34(+) stem/progenitor cells
We have analyzed the pattern of gene expression in human primary CD34(+) stem/progenitor cells. We identified 42,399 unique serial analysis of gene expression (SAGE) tags among 106,021 SAGE tags collected from 2.5 x 10(6) CD34(+) cells purified from bone marrow. Of these unique SAGE tags, 21,546 mat...
ORGANISM(S): Homo sapiens 
2005-02-28 | E-GEOD-2346 | biostudies-arrayexpress
ProteomicsLong noncoding RNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5
Cisplatin resistance is a major therapeutic challenge in advanced head and neck squamous cell carcinoma (HNSCC). Here, we aimed to investigate the key signaling pathway for cisplatin resistance in HNSCC cells. HNSCC cell lines that were sensitive (HN4 and HN30) or resistant (HN4/DDP and HN30/DDP) to...
ORGANISM(S): Homo Sapiens 
2020-11-28 | PXD022799 |
ProteomicsIdentification of Escherichia coli FH-binding proteins
This project used biotin pull-down to screen membrane proteins with FH binding function from the membrane proteins of Escherichia coli RS218. It contained an experimental group (SHIYANZU1) and a control group (DUIZHAOZU)..
ORGANISM(S): Escherichia Coli Rs218 
2020-07-23 | PXD020521 |
UnknownRestored CD8+PD-1+ T Cells Facilitate the Response to Anti-PD-1 for Patients With Pancreatic Ductal Adenocarcinoma.
Not available
S-EPMC9035626 | biostudies-literature
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