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TranscriptomicsZfp281 Coordinates Opposite Functions of Tet1 and Tet2 for Alternative Pluripotent States
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-06-28 | E-GEOD-81045 | biostudies-arrayexpress
TranscriptomicsTex10 Coordinates Epigenetic Control of Super-Enhancer Activity for Pluripotency and Reprogramming
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-05-06 | E-GEOD-66736 | biostudies-arrayexpress
ProteomicsTET1 interactome by SILAC IP-MS in mouse ESCs
TET1 maintains hypomethylation at bivalent promoters through its catalytic activity in embryonic stem cells (ESCs). However, whether and how TET1 exerts catalytic activity-independent functions in regulating bivalent genes is not well understood. Therefore, we mapped the TET1 interactome in mouse ES...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-10 | PXD033587 | Pride
Silac Ip-ms Tet1 Escs 
ProteomicsOCT4 IP-MS in Naive and Primed Human ESCs
Understanding the molecular underpinnings of pluripotency is a prerequisite for optimal maintenance and application of embryonic stem cells (ESCs). While the protein-protein interactions of core pluripotency factors have been identified in mouse ESCs, their interactome in human ESCs (hESCs) has not ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-12 | PXD026556 | Pride
Oct4 Esc 
UnknownSynthesis and Application of Ion-Exchange Magnetic Microspheres for Deep Removal of Trace Acetic Acid from DMAC Waste Liquid.
Not available
S-EPMC9918990 | biostudies-literature
ProteomicseIF4A3 interactome by IP-MS in mouse ESCs
RNA helicases are involved in multiple steps of RNA metabolism to direct their roles in gene expression, yet their functions in pluripotency control remain largely unexplored. Starting from an RNAi screen of RNA helicases, we identified that eIF4A3, a DEAD-box (Ddx) helicase component of the exon ju...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031362 | Pride
Ip-ms Eif4a3 Escs 
TranscriptomicsZfp281 Coordinates Opposite Functions of Tet1 and Tet2 for Alternative Pluripotent States [RNA-Seq]
Pluripotent cell identity comprises a spectrum of cell states including naive and primed states, which are typified by mouse embryonic stem cells (ESCs) and epiblast-derived stem cells (EpiSCs), respectively. Here we define a pluripotent cell fate (PCF) gene signature based on RNA-seq analysis assoc...
ORGANISM(S): Mus musculus 
2016-06-28 | E-GEOD-81044 | biostudies-arrayexpress
GenomicsZfp281 Coordinates Opposite Functions of Tet1 and Tet2 for Alternative Pluripotent States [ChIP-Seq]
Pluripotent cell identity comprises a spectrum of cell states including naive and primed states, which are typified by mouse embryonic stem cells (ESCs) and epiblast-derived stem cells (EpiSCs), respectively. Here we define a pluripotent cell fate (PCF) gene signature based on RNA-seq analysis assoc...
ORGANISM(S): Mus musculus 
2016-06-28 | E-GEOD-81042 | biostudies-arrayexpress
GenomicsTex10 Coordinates Epigenetic Control of Super-Enhancer Activity for Pluripotency and Reprogramming [ChIP-Seq]
Super-enhancers (SEs) are large clusters of transcriptional enhancers that are co-occupied by multiple lineage specific transcription factors driving expression of genes that define cell identity. In embryonic stem cells (ESCs), SEs are highly enriched for Oct4, Sox2, and Nanog in the enhanceosome a...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-66735 | biostudies-arrayexpress
TranscriptomicsTex10 Coordinates Epigenetic Control of Super-Enhancer Activity for Pluripotency and Reprogramming [RNA-Seq]
Super-enhancers (SEs) are large clusters of transcriptional enhancers that are co-occupied by multiple lineage specific transcription factors driving expression of genes that define cell identity. In embryonic stem cells (ESCs), SEs are highly enriched for Oct4, Sox2, and Nanog in the enhanceosome a...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-66734 | biostudies-arrayexpress
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