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ProteomicsTMT-Based Quantitative Proteomic Profiling of Retina, Choroid, and Sclera in Albino and Pigmented Guinea Pigs to Investigate Myopia Susceptibility and Pathogenesis
Myopia development and susceptibility vary across pigmentation backgrounds and ocular tissues, yet the underlying molecular mechanisms remain unclear. In this study, retina, choroid, and sclera were collected from albino and pigmented guinea pigs subjected to spontaneously developed hyperopia and my...
ORGANISM(S): Cavia porcellus (Guinea pig) 
2026-08-24 | PXD069847 | Pride
Guinea pig Myopia Proteomics Sclera Choroid Retina 
ProteomicsUncovering protein regulation during adventitious root formation in Platycladus orientalis cuttings
Cell totipotency and pluripotency are the cellular basis for root regeneration in Platycladus orientalis cuttings, and the regeneration of adventitious roots is a key determinant for improving stem-cutting. However, the cellular basis and physiological regulation of adventitious root formation are s...
ORGANISM(S): Platycladus Orientalis 
2024-05-24 | PXD052541 |
TranscriptomicsMulti-organ mapping of cancer risk
Cancers are distributed unevenly across the body; but the importance of cell intrinsic factors such as stem cell function in determining organ cancer risk is unknown. Therefore, we used cre-recombination of conditional lineage tracing, oncogene and tumour suppressor alleles to define populations of...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-78076 | biostudies-arrayexpress
ProteomicsIdentification of p72-interacting proteins in porcine alveolar macrophages
To explore the potential mechanisms regulating p72 stability, we performed co-immunoprecipitation using an anti-p72 antibody in ASFV-infected PAMs, followed by mass spectrometry analysis to identify host factors interacting with p72.
ORGANISM(S): Sus Scrofa Domesticus 
2026-01-18 | PXD073232 |
Proteomicsproteomic analysis in cataract of Ailuropoda melanoleuca (Giant panda)
proteomic analysis between cataract of Ailuropoda melanoleuca (Giant panda) and normal panda
ORGANISM(S): Ailuropoda Melanoleuca 
2022-01-18 | PXD031039 |
TranscriptomicsCancers originate preferentially in adult tissue stem cells
Stem cells have long been regarded as a potential origin of cancer. But cancers could also arise from mutated, differentiated cells that reacquire stem cell properties. Here, in mice harboring conditional oncogenic and lineage tracing alleles, we show that cancers develop from Prom1+ (CD133) cells...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-40634 | biostudies-arrayexpress
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