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ARMMs (arrestin domain-containing protein 1 [ARRDC1]-mediated microvesicles) are extracellular vesicles that bud directly atthe plasma membrane. However, little is known about the physiological function of these vesicles. Here we report that secreted ARMMs contain active NOTCH receptors and mediate ...
ORGANISM(S): Homo sapiens (Human) 
2017-10-11 | PXD006416 | Pride
Neurosyphilis (NS) is a clinical condition caused by infection of the central nervous system (CNS) by Treponema pallidum (Tp) that can lead to asymptomatic meningitis and more serious neurological diseases, such as dementia and blindness. However, current studies on the pathogenesis of NS are limite...
ORGANISM(S): Homo Sapiens 
Spatial proteins expression is critical to identify exactly protein localization and function in tissues. By combining decellularization, laser-capture microdissection, and mass spectrometry, six different partitioned proteins among skin layers of stratum corneum (SC), granular-spinous (GS), basal l...
ORGANISM(S): Homo Sapiens 
2021-07-05 | PXD027093 |
Skin aging is a physiological problem that remains a concern. Studies have demonstrated that the dermal extracellular matrix (ECM) plays important roles in skin aging; however, changes in ECM characteristics and molecules that are secreted to the extracellular space and involved in the formation of ...
ORGANISM(S): Homo Sapiens 
2022-11-28 | PXD016440 |
Scleroderma is a chronic connective tissue disease characterized by skin thickening and plaque morphea, as well as hard, shiny skin. Serious involvement is observed from the superficial dermis down to the fascia and muscle. However, this condition is difficult to treat and evaluate. In this study, i...
ORGANISM(S): Mus Musculus 
To find baseline markers that accurately predict vaccine reactivity and evaluate the correlation between baseline blood and urine proteomics and antibody titers after COVID-19 vaccination.
ORGANISM(S): Homo Sapiens 
2023-11-09 | PXD036380 |
proteomic data of XopR-mRuby2-TurboID and mRuby2-TurboID labelled proteins
ORGANISM(S): Arabidopsis Thaliana 
Neurosyphilis (NS) is a central nervous system infection caused by Treponema pallidum. NS can occur at any stage of syphilis and manifests as a broad spectrum of clinical symptoms. Often referred to as “the great imitator”, NS can be easily overlooked or misdiagnosed due to the absence of standard d...
ORGANISM(S): Homo Sapiens 
2024-02-16 | PXD033034 |
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