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MetabolomicsBlood pseudotargeted metabolome of moyamoya disease

We aimed to identify specific metabolomic changes and biomarkers for the differential clinical diagnosis of different subtypes of moyamoya disease (MMD). We conducted an pseudotargeted metabolomics analysis and pseudotargeted metabolomics analysis revealed decreased LPC expression in patients wit...

2024-10-31 | MTBLS10304 | MetaboLights
ProteomicsDisruption of Iron Homeostasis Sensitizes Pancreatic Cancer to Irreversible Electroporation
Quantitative proten expression in Panc-1 cells treated with MOF-Fe and a Ferritin Degrader
ORGANISM(S): Homo Sapiens 
2025-04-30 | PXD063472 |
ProteomicsSerum proteome analysis identifies a potential biomarker for axial psoriatic arthritis
Serum samples were collected from patients with PsA to create a biomarker discovery cohort and a validation cohort. Patients with PsA were classified into axial or peripheral subtypes based on imaging criteria. Liquid chromatography-mass spectrometry was used in the discovery phase to screen for bio...
ORGANISM(S): Homo Sapiens 
2023-08-16 | PXD044598 |
ProteomicsTandem Mass Tag-based proteomics of astaxanthin-producing tobacco expressing astaxanthin synthetases from Adonis aestivalis
The synthesis of astaxanthin leads to growth retardation in tobacco. Meanwhile, irregular mosaic pigmentation randomly appears on the leaves of astaxanthin-producing tobacco. The purpose of this project is to elucidate the mechanism of growth retardation in astaxanthin-producing tobacco and to compa...
ORGANISM(S): Nicotiana Tabacum 
2024-03-05 | PXD050349 |
ProteomicsDenervated muscle promotes nerve regeneration via retrograde metabolic signaling, revising the neural-dominated view of neuromuscular interactions
Peripheral nerve injury causes muscle atrophy due to slow axonal regeneration, highlighting an unmet therapeutic need. Although neuromuscular interactions are classically viewed as unidirectionally nerve-dominated, we show that acutely denervated muscle (adMu) regulates nerve regeneration via a retr...
ORGANISM(S): Mus Musculus 
2025-12-02 | PXD071459 |
ProteomicsLabel-free quantitative proteomics for screening dynamic autophagy-related proteins during nutrient deprivation in MEFs
A Label-free quantitative proteomic profiling was performed on MEFs with or without nutrient starvation.
ORGANISM(S): Mus Musculus 
2022-10-15 | PXD025450 |
ProteomicsProteomic analysis of Hypsibius henanensis sp.nov. suffered from 12C6+ heavy ion radiation based on label-free technology
Tardigrades are a kind of species that can tolerate ultra-high doses of ionizing radiation. Here, we used heavy ions at different doses of 0,200 and 2000Gy to irradiate Hypsibius henanensis sp.nov.. Label-free proteomic identification was performed on the samples, each dose containing 3 repetitions
ORGANISM(S): Tardigrada 
2023-09-20 | PXD045537 |
ProteomicsDetection of betalains from the extracts of H. henanensis sp. nov.
Identification of betalains from the extracts of H. henanensis sp. nov. using untargeted metabolomics.
ORGANISM(S): Tardigrada 
2024-03-22 | PXD050882 |
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