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TranscriptomicsmRNA-seq data from embryonic autopods of the common bent-wing bat (Miniopterus schreibersii)
The only freely flying mammals, bats, develop a pair of dramatically elongated hands and broad wing membranes. It is hypothesized that alterations of many gene expressions result in the bat wing formation. However, it remains to be proved. Here, by mRNA-seq, we found that hundreds of genes are signi...
ORGANISM(S): Miniopterus schreibersii 
2014-04-14 | E-GEOD-50699 | biostudies-arrayexpress
ProteomicsMettl1-mediated B cell responses
Germinal center (GC) response requires increased protein synthesis. We identify the methyltransferase METTL1 as a translational checkpoint during GC responses. Therefore, we immunized mettl1-cko mice and control mice with NP-OVA, and sorted spleen B cells on day 14.
ORGANISM(S): Mus musculus (Mouse) 
2024-11-01 | PXD057426 | Pride
Mice B cells Spleen 
MetabolomicsA gut Eggerthella lenta–derived metabolite impairs neutrophil function to aggravate bacterial lung infection
The “gut-lung” axis is crucial for the chronic infection in bronchiectasis. However, the responsible microbe and the mechanism in the “gut-lung” axis of bronchiectasis are still in demand for precise elucidation. Here, we reported that Eggerthella lenta in the gut and taurine ursodeoxycholic acid (T...
2025-02-27 | MTBLS9522 | MetaboLights
TranscriptomicsDigital gene expression tag profiling of digit morphologies in bats
As the only truly flying mammals, bats use their unique wing formed from elongated digits connected by membranes to power their flight. The forelimb of bats consists of four elongated digits (digits II-V) and one shorter digit (digit I) that is morphologically similar to the hindlimb digits. Elongat...
ORGANISM(S): Myotis ricketti 
2010-12-06 | E-GEOD-20038 | biostudies-arrayexpress
ProteomicsEVA1A responds to endoplasmic reticulum stress to regulate renal fibrosis by promoting TGF-β signaling pathway
LC-MS results of EVA1A and TGFBR2 pulldown counterpart in 293T cells
ORGANISM(S): Homo Sapiens 
2025-12-09 | PXD071738 |
ProteomicsEcN OMVs mass spectrometry proteomics data
The mass spectrometry proteomics data of outer membrane vesicles of wide-type Escherichia coli Nissle 1917 and engineered Escherichia coli Nissle 1917
ORGANISM(S): Escherichia Coli 
PXD053377 |
ProteomicsLC/MS Data for Human CD4+ T cells
For metabolic profiling of human CD4+ T cells，stable isotope labeling (SIL) and metabolomics SIL experiments were performed with in vitro-activated T cells using liquid chromatography (LC) coupled to mass spectrometry (MS).
ORGANISM(S): Homo Sapiens 
PXD055329 |
ProteomicsGC/MS data for mouse spleen CD4+ T cells
For metabolic profiling of mouse CD4+ T cells, stable isotope labeling (SIL) experiments were performed with in vitro-activated T cells using gas chromatography (GC) coupled to mass spectrometry (MS).
ORGANISM(S): Mus Musculus 
PXD055328 |
TranscriptomicsKaplan2013: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II
Dynamic control of gene expression is crucial for most aspects of cell physiology and at its core is RNA polymerase II (RNAPII). Using 53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) comprising ~60,000 quantitative genetic interactions in Saccharomyces cere...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-06 | E-GEOD-47429 | biostudies-arrayexpress
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