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The details of Toll-like receptor (TLR) 4 signaling affects protein succinylation in intracerebral hemorrhage (ICH) brains remains completely unclear. In this study, we constructed mice ICH models to investigate the changes in ICH-associated brain protein succinylation with the treatment of TLR4 ant...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD025622 | Pride
One bottleneck in understanding the principles of 3D chromatin structures is caused by the paucity of known regulators. Cohesin is essential for 3D chromatin organization, and its interacting partners are candidate regulators. Here, we performed proteomic profiling of the Cohesin in chromatin and id...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-06-05 | PXD028860 | Pride
To explore the mechanism of pachytene pirna biogenesis, we employed a proteomics approach using flag-tagged adad2 transgenic mice expressed fully functional N-terminal epitope-tagged HA-ADAD2 and performed anti-FLAG immunoprecipitation coupled with quantitative mass spectrometry (IP-MS) from testis ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-14 | PXD034437 | Pride
To explore the mechanism of pachytene pirna biogenesis, we performed anti-RNF17 immunoprecipitation coupled with quantitative mass spectrometry (IP-MS) from testis extracts of adult mice.
ORGANISM(S): Mus musculus (Mouse) 
2023-03-14 | PXD034463 | Pride
The intriThe intricate balance between MSCs differentiation to osteoblasts or adipocytes is finely regulated. To explore novel participating molecules, we screened for early-stage osteogenesis- or adipogenesis-based MSCs protein expression profile using TMT-based quantitative proteomic analysis. Pro...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041404 | Pride
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