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UnknownEngineering an Autonucleolytic Mammalian Suspension Host Cell Line to Reduce DNA Impurity Levels in Serum-Free Lentiviral Process Streams.
Not available
S-EPMC10877604 | biostudies-literature
UnknownBVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeability.
Not available
S-EPMC6162166 | biostudies-literature
TranscriptomicsCUT&RUN experiment at four time points in HEK293T and hESC cells, assessing the time-resolved response of β-catenin genomic occupancy upon Wnt signaling activation
Wnt/β-catenin signaling is a highly organized biochemical cascade that triggers a gene expression program in the signal-receiving cell. The Wnt/β-catenin-driven transcriptional response is involved in virtually all cellular processes during development, homeostasis, and its deregulation causes human...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-12077 | biostudies-arrayexpress
TranscriptomicsATAC-seq experiment at four time points in HEK293 and hESC cells, assessing the time-resolved response on chromatin accessibility upon Wnt/β-catenin signaling activation
Wnt/β-catenin signaling is a highly organized biochemical cascade that triggers a gene expression program in the signal-receiving cell. The Wnt/β-catenin -driven transcriptional response is involved in virtually all cellular processes during development, homeostasis, and its deregulation causes huma...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-12076 | biostudies-arrayexpress
UnknownSequence segregation improves non-covalent protein delivery.
Not available
S-EPMC5568762 | biostudies-literature
ProteomicsPyrin oligomerization nucleates antiviral IFI16 sensing of herpesvirus DNA
The formation of multimerized protein assemblies has emerged as a core component of immune signal amplification, yet the biochemical basis of this phenomenon remains unclear for many mammalian proteins within host defense pathways. The interferon-inducible protein 16 (IFI16) is a viral DNA sensor th...
ORGANISM(S): Homo sapiens (Human) 
2019-07-10 | PXD014349 | Pride
Ifi16 Ip-ms Dna sensing Hsv-1 Oligomerization 
GenomicsMolecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor
PRJNA578614 | ENA
ProteomicsMultiomic analysis of Cohesin reveals that ZBTB transcription factors contribute to chromatin interactions
One bottleneck in understanding the principles of 3D chromatin structures is caused by the paucity of known regulators. Cohesin is essential for 3D chromatin organization, and its interacting partners are candidate regulators. Here, we performed proteomic profiling of the Cohesin in chromatin and id...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-06-05 | PXD028860 | Pride
Human Label-free Mouse Hek293ts Chip-ms Mescs 
ProteomicsMultiomic analysis of Cohesin reveals that ZBTB transcription factors contribute to chromatin interactions
One bottleneck in understanding the principles of 3D chromatin structures is caused by the paucity of known regulators. Cohesin is essential for 3D chromatin organization, and its interacting partners are candidate regulators. Here, we performed proteomic profiling of the Cohesin in chromatin and id...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-05 | PXD036004 | Pride
Human Ch12f3 Label-free Mouse Hek293ts Chip-ms B16 Mescs 
ProteomicsMultiomic analysis of Cohesin reveals that ZBTB transcription factors contribute to chromatin interactions
One bottleneck in understanding the principles of 3D chromatin structures is caused by the paucity of known regulators. Cohesin is essential for 3D chromatin organization, and its interacting partners are candidate regulators. Here, we performed proteomic profiling of the Cohesin in chromatin and id...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-05 | PXD035893 | Pride
Human Ch12f3 Label-free Mouse Hek293ts Chip-ms B16 Mescs 
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