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Distinct genotypic and pathogenicity differences exist between strains of the opportunistic protozoan Toxoplasma gondii. The label-free quantitative acetylomics approach was applied to investigate the differences in the level of acetylation between RH strain, PRU strain and PYS strain of T. gondii. ...
ORGANISM(S): Toxoplasma 
2020-05-27 | PXD015031 | Pride
Phosphorylation is a regulatory mechanism by which intracellular apicomplexan parasites control the process of invading and modifying host cells. However, the sporulated oocysts’ phosphoprotein repertoires between virulent and avirulent strains of Toxoplasma gondii and the underlying mechanisms cont...
ORGANISM(S): Toxoplasma gondii 
2022-02-22 | PXD017032 | Pride
Understanding of protein expression difference in the same stage of T.gondii among different genotypes will facilitate the elucidation of genotypic divergence among the T.gondii strains. A 4-plex iTRAQ (isobaric tag for relative and absolute quantitation) based LC-MS/MS approach was employed to surv...
ORGANISM(S): Toxoplasma gondii 
2018-10-26 | PXD005928 | Pride
iTRAQ technology combine with titanium dioxide (TiO2) affinity chromatography was applied to investigate the phosphoproteomic difference between type I (RH) strain, type II Prugniuad (PRU) strain and Chinese 1 (PYS) strain genotypic tachyzoites of T. gondii
ORGANISM(S): Toxoplasma gondii 
2019-11-14 | PXD007777 | Pride
Toxoplasma gondii threats to the health of one-third of the world's population. Cat is the natural definite host of T. gondii. However, the biological changes of feline small intestine following T. gondii infection remains mysterious event. Protein acetylation modification which is a dynamic and rev...
ORGANISM(S): Felis Catus 
In this study, we established a type 2 diabetes model in C57BL/6 mice through high-fat diet induction and STZ injection. Based on this animal model, we simulated clinically common hard-to-heal chronic diabetic skin wounds by implanting a mixed bacterial fluid, including Methicillin-resistant Staphyl...
ORGANISM(S): Mus Musculus 
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