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UnknownSensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins.
Not available
S-EPMC6290684 | biostudies-literature
UnknownImpact of antiretroviral therapy in primary HIV infection on natural killer cell function and the association with viral rebound and HIV DNA following treatment interruption.
Not available
S-EPMC9468877 | biostudies-literature
TranscriptomicsTranscription profiling of dab hepatocellular adenoma liver tumours (Limanda limanda)
A custome-made 8x15k oligonucleotide limanda limanda microarray (Agilent) comprised of 14919 experimental probes, was used to characterize gene expression profiles of dab hepatocellular adenoma tumours from sites of different pollution status in Irish Sea.
ORGANISM(S): Limanda limanda 
2011-11-04 | E-MTAB-734 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from immature Platichthys flesus treated with model toxicants
Using the GENIPOL flounder cDNA microarray, we assessed the temporal transcriptomic responses of Platichthys flesus to model toxicants over a 16 day timespan. Immature fish were treated by intraperitoneal injection with cadmium chloride (50 micrograms/kg in saline), 3-methylcholanthrene (25mg/kg in ...
ORGANISM(S): synthetic DNA 
2009-06-16 | E-MAXD-32 | biostudies-arrayexpress
ProteomicsAssociation of Drosophila Polyhomeotic (Ph) and Ph-PHC3 chimeras with PRC1 components in human cells
To determine if ectopically expressed Venus-tagged Polyhomeotic/PHC3 proteins assemble into PRC1 in human cells, we carried out immunoprecipitations with anti-GFP resin followed by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD060324 | Pride
Human flp-in t-rex 293 Co-immunoprecipitation Prc1 Lc-ms/ms 
TranscriptomicsMolecular responses of European flounder (Platichthys flesus) chronically exposed to contaminated estuarine sediments
Flounder fish were exposed in mesocosms for seven months to a contaminated estuarine sediment made by mixing material from the Forth (high organics) and Tyne (high metals and tributyltin) estuaries (FT) or control sediment from the Ythan estuary (Y). Their gene expression profiles were compatred by ...
ORGANISM(S): Platichthys flesus 
2014-03-01 | E-MTAB-1847 | biostudies-arrayexpress
ProteomicsMoyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism
RNF213 is the major susceptibility factor for Moyamoya disease, a progressive cerebrovascular disorder that often leads to brain stroke in adults and children. Characterization of disease-associated mutations has been complicated by the enormous size of RNF213. Here we present the cryo-EM structure ...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-24 | PXD018701 | Pride
Rnf213 Mouse E3-ligase 
ProteomicsUNC-45 assisted myosin folding depends on a conserved FX3HY motif implicated in Freeman Sheldon Syndrome
Myosin motors are critical for diverse motility functions ranging from cytokinesis and endocytosis to muscle contraction. The UNC-45 chaperone controls myosin function mediating the folding, assembly, and degradation of the muscle protein. Here, we analyze the molecular mechanism of UNC-45 as a hub ...
ORGANISM(S): Caenorhabditis elegans 
2024-07-25 | PXD040428 | Pride
Ufd-2 Myopathy Mhc-b Myo4 Protein quality control Crosslinking mass spectrometry Ubiquitin proteasome system Unc-45 Molecular chaperones Myosin proteostasis 
TranscriptomicsPtrA is required for coordinate regulation of gene expression during phosphate depletion in a marine Synechococcus
The genome of the marine Synechococcus sp. WH8102 displays a minimal regulatory network yet physiological and molecular responses of this organism are tuned to episodic limitation for nitrogen and phosphorus. Microarray analyses have demonstrated a key role for the two-component regulatory system, P...
ORGANISM(S): Synechococcus sp. WH 8102 
2010-04-08 | E-GEOD-18511 | biostudies-arrayexpress
ProteomicsBioID with P. falciparum protein PhiL1
The aim of the project was to identify proteins proximal to Plasmodium falciparum PhiL1
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-05-03 | PXD024237 | Pride
Lc-msms Plasmodium falciparum Phil1 
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