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Label Free Quantification (LFQ) of shotgun proteomics data is a popular and robust method for the characterization of relative protein abundance between samples. Many analytical pipelines exist for the automation of this analysis and some tools exist for the subsequent representation and inspection ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2022-04-13 | PXD028038 | Pride
This study aimed to characterise the protein that a novel compound binds to, thus promoting its ability to inhibit BAK apoptotic activity.
ORGANISM(S): Homo sapiens (Human) 
2019-10-11 | PXD013129 | Pride
Repair after damage is essential for tissue homeostasis. Post-menstrual repair of the uterine endometrium is a unique cyclical manifestation of rapid, scar-free, tissue repair taking ~3-5 days. Skin repair post-wounding is slower (~2 weeks) and, in the case of chronic wounds, takes months/years to r...
ORGANISM(S): Homo sapiens (Human) 
2018-07-30 | PXD007234 | Pride
Selecting a sample preparation strategy for mass spectrometry-based proteomics is critical to the success of quantitative workflows. Here we present a universal, solid-phase protein preparation (USP3) method which is rapid, robust and scalable, facilitating high-throughput protein sample preparation...
ORGANISM(S): Homo sapiens (Human) 
2019-06-05 | PXD011169 | Pride
Diagnosis of ovarian cancer at an early stage is the most important determinant of survival. Thus, there is a clear need for novel biomarkers to improve diagnostic and prognostics that may better inform on therapeutic strategies. We have conducted a discovery study using label-free quantitative mass...
ORGANISM(S): Homo sapiens (Human) 
2018-02-15 | PXD007962 | Pride
Research in urine proteomics and extracellular vesicles (EV) has gained increasing traction in biomarker research. Previous studies have suggested that both can be affected by urine protein concentration, however, there is a lack of data on the combined effect on urine proteomics. Here, we assessed ...
ORGANISM(S): Homo sapiens (Human) 
2025-07-11 | PXD056692 | Pride
Missed identifications of peptides in data-dependent acquisition (DDA) proteomics experiments is an obstacle n the precise determination of which proteins are present in a sample and their relative abundance. Efforts pular analysis workfl raw data to transfer a pehtiraw identifiher. Another approach...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2022-03-07 | PXD030706 | Pride
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