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To identify the candidate that directly stabilizes G3BP1 mRNA, the enriched proteins pulled down by G3BP1 probes and anti-RAN antibody were subjected to mass spectrometry (MS) analysis
ORGANISM(S): Homo Sapiens 
Mouse of SiO2 group were instilled with silica suspension, and mouse of control group were instilled with NS. The mouse mouse were raised for 56 d, and then the ECM was harvest. We found out the main protein deposited in fabrotic lung ECM. By spatial transcriptomics, we analyzed the distribution pat...
ORGANISM(S): Mus Musculus 
Cell membranes harvested from U251 and primary healthy astrocytes were prepared for LC-MS/MS analysis. After analysis, we could obtain a pool of proteins, which were enriched in the U251 cell membrane sample rather than healthy astrocyte membrane sample.
ORGANISM(S): Homo Sapiens 
2022-01-06 | PXD030760 |
Our study identify that methionine inhibits N-terminus of GSDME (GSDME-NT) -mediated pyroptosis by dampening its endocytotic degradation. This process is regulated by methionine metabolite spermidine,which can bind with proteins to regulate their biological function. Thus,the binding proteins of sp...
ORGANISM(S): Homo Sapiens 
2025-01-21 | PXD060003 |
Our study identify that methionine inhibits N-terminus of GSDME (GSDME-NT) -mediated pyroptosis by dampening its endocytotic degradation. Thus,the binding proteins of GSDME-NT are detected in the presence or absence of Methionine for futher exploration。
ORGANISM(S): Homo Sapiens 
2025-01-19 | PXD059954 |
We employ Mass spectrum to investigate proteome of Pum1-Knockout, Pum2-Knockout and WT conditions in human colorectal cancer cell line Hct116. Overall design: In order to investigate whether Pum1 and Pum2 regulate their targets at their protein levels, we used Pum1-Knockout, Pum2-Knockout and WT Hct...
ORGANISM(S): Homo Sapiens 
2021-07-23 | PXD027513 |
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