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MetabolomicsNon-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome
INTRODUCTION: Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring in the first 3 months of life. The most common causes of neonatal cholestasis are infantile hepatitis syndrome (IHS) and biliary atresia (BA). The clinical manifestations of the two diseases are ...
2019-06-25 | MTBLS689 | MetaboLights
UnknownExperimental infection of Z:ZCLA Mongolian gerbils with human hepatitis E virus.
Not available
S-EPMC4299338 | biostudies-literature
UnknownDownregulation of KIF1B mRNA in hepatocellular carcinoma tissues correlates with poor prognosis.
Not available
S-EPMC4507112 | biostudies-literature
TranscriptomicsCXCR5+ Follicular Cytotoxic T cells Control Viral Infection in B Cell follicles
Lymphocytic Choriomeningitis Virus (LCMV) specific CD8+ T cells (P14) were transferred into congenic WT mice followed by LCMV(DOCILE) infection. CXCR5-expressing (CXCR5+) or CXCR5 non-expressing (CXCR5-) P14 were purified on day 8 after infection, and total mRNA were sequenced from these populations...
ORGANISM(S): Mus musculus 
2016-07-31 | E-GEOD-76279 | biostudies-arrayexpress
ProteomicsA Universal 384-Well Proteomic Sample Preparation Platform for High-Throughput Screening and Biomarker Discovery
Major advances have been made to improve the sensitivity of mass analyzers, spectral quality, and the speed of data processing enabling more comprehensive proteome discovery and quantitation. While focus has recently begun shifting toward robust proteomic sample preparation efforts, a high throughpu...
ORGANISM(S): Homo sapiens (Human) 
2021-06-14 | PXD023374 | Pride
High-throughput Hplc-ms/ms Proteomics Biomarker Compound screen 
ProteomicsA Universal 384-Well Proteomic Sample Preparation Platform for High-Throughput Screening and Biomarker Discovery
Major advances have been made to develop an automated universal 384-well plate sample preparation platform with high reproducibility and adaptability for extraction of proteins from cells within a culture plate. An in-solution digest strategy is employed to generate peptides from the extracted prote...
ORGANISM(S): Homo sapiens (Human) 
2021-06-14 | PXD019733 | Pride
Proteomics Hplc-ms Mrm High-throughput screening Biomarkers 
ProteomicsUSP20 promotes T-ALL evolution by deubiquitinating modified HIF1A
Qualitative analysis of proteome is to study the types and quantities of proteome identified by samples under different conditions, and to perform functional analysis of the identified proteins, so as to provide reference information for quantitative and modification analysis of high-throughput prot...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD053080 | Pride
Usp20 Hif1a 
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
UnknownProtein kinase 2 (CK2) controls CD4+ T cell effector function in the pathogenesis of colitis.
Not available
S-EPMC7382987 | biostudies-literature
TranscriptomicsExpression data from human lymphoma endothelium and reactive lymph node-derived endothelium
Angiogenesis plays a key role in tumor metastasis. Many genes may act in this process including formation of vessels, immune evasion,etc. Different gene expression profiles between lymphoma endothelium cells and reactive lymph node-derived endothelium cells may uncover these genes. And intensive mec...
ORGANISM(S): Homo sapiens 
2010-01-14 | E-GEOD-19882 | biostudies-arrayexpress
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