Sort   by:  
 Page size 
ModelsBucher2011_Atorvastatin_Metabolism
This is the model of atorvastatin metabolism in hepaitc cells described in the article: A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes Joachim Bucher , Stephan Riedmaier , Anke Schnabel , Katrin Marcus , G...
2024-09-02 | BIOMD0000000328 | BioModels
UnknownProspective, observational study of pain and analgesic prescribing in medical oncology outpatients with breast, colorectal, lung, or prostate cancer.
Not available
S-EPMC3383175 | biostudies-literature
UnknownRituximab extended schedule or re-treatment trial for low-tumor burden follicular lymphoma: eastern cooperative oncology group protocol e4402.
Not available
S-EPMC4171355 | biostudies-literature
GenomicsChIP-Seq data from Nup133 ChIP performed on primary male and female mouse derived oligodendrocyte precursor cells
Nup133 is known to play a crucial role in neural cell differentiation. But its downstream targets and the exact mechanisms of its action are largely unknown. Hence, we performed targeted chromatin immunoprecipitation experiments followed by next generation sequencing to identify its genomic targets....
ORGANISM(S): Mus musculus 
2020-09-16 | E-MTAB-7332 | biostudies-arrayexpress
TranscriptomicsNuclear SLIC-CAGE of human cortical neurons from Cornelia de Lange Syndrome patients and control individuals
We used SLIC-CAGE to map transcriptional start sites in cortical neurons from Cornelia de Lange Syndrome (CdLS) patients and control individuals. SLIC-CAGE was performed using nuclear RNA isolated from pre-frontal cortical grey matter. Usage of nuclear RNA allows enrichment of unstable RNAs, such as...
ORGANISM(S): Homo sapiens 
2021-02-27 | E-MTAB-9045 | biostudies-arrayexpress
ProteomicsProteomic dissection of human erythropoiesis reveals critical roles of kinases
Human erythropoiesis is exquisitely controlled at multiple levels and its dysregulation leads to anemias and many other diseases. We apply mass spectrometry (MS)-based proteomics to comprehensively investigate the protein and signaling dynamics of this process. Mapping the proteomes and phosphoprote...
ORGANISM(S): Homo sapiens (Human) 
2020-10-20 | PXD017276 | Pride
Ckit Red blood cells Hematopoietic stem and progenitor cells Differentiation Mapk Phosphoproteomics Epor Human erythropoiesis Proteomics Development Kinase Systems biology Signaling 
UnknownTranslation of mouse model to human gives insights into periodontitis etiology.
Not available
S-EPMC7078197 | biostudies-literature
ProteomicsThe proteomic landscape of proteotoxic stress in a fibrogenic liver disease
Protein misfolding diseases, including alpha-1 antitrypsin deficiency (AATD), pose significant health challenges, yet their progression at the cellular level remains poorly understood. Here, we employ spatial proteomics by mass spectrometry and machine learning to map the molecular landscape of AATD...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD054440 | Pride
Alpha-1 antitrypsin deficiency Proteotoxic stress Single cell Deep visual proteomics Liver 
ProteomicsInteracting proteins on lncRNA SMANTIS in THP-1 cells
The lncRNA SMANTIS (formerly known as MANTIS, AK125871, n342419) functions as a regulator of cell function in endothelial cells and for adhesion to monocytes. Here, we investigated the function of SMANTIS in THP-1 monocytes. By using an antisense oligonucleotide pulldown approach followed by LC/MS, ...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD048847 | Pride
Monocytes Complex remodeling Lncrna Protein-rna complexes 
ProteomicsDynamic of the Grb2 interactome in primary cells by DDA-MS
We applied AP-MS to quantify Grb2 interaction dynamics in primary T cells. Data generated here in shotgun/DDA mode were used to build a high quality Grb2 binders-specific SWATH assay library for high-throughput targeted analysis of DIA data.
ORGANISM(S): Mus musculus (Mouse) 
2017-03-09 | PXD003973 | Pride
Primary t cells Ms Grb2 Interactome Dda 
Sort   by:  
 Page size