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TranscriptomicsThe Complete Genome of a Single Individual by Massively Parallel DNA Sequencing
The association of genetic variation with disease and drug response, together with improvements in nucleic acids technologies, has given great optimism for the impact of 'genomic medicine'. However, the formidable size of the diploid human genome has prevented the routine application of sequencing ...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10668 | biostudies-arrayexpress
UnknownRacial/Ethnic Disparities In COVID-19 Exposure Risk, Testing, And Cases At The Subcounty Level In California.
Not available
S-EPMC8458028 | biostudies-literature
ProteomicsQuantitative differences in rumen epithelium proteins, as well as body composition and metabolizable energy intake in lambs fed a low or high energy diet.
The rumen is a major the site of digestion and absorption of energy predominantly in the form of short chain fatty acids as well as amino acids and simple carbohydrates. The research sought to determine if diets high or low in ME were associated with quantitative changes in the membrane bound protei...
ORGANISM(S): Ovis aries 
2026-02-09 | PXD054700 | Pride
Epithelium Nutrient Transport Rumen Membrane 
TranscriptomicsGene expression profiles of LPS-stimulated RAW264.7 macrophages overexpressing Tbc1d23 novel innate immune gene
We previously identified Tbc1d23 as a candidate novel regulator of innate immunity using comparative genomics RNAi screens in C. elegans and mouse macrophages. Using mice with an engineered knockout mutation in Tbc1d23 and macrophages engineered to overexpress Tbc1d23, we now show that Tbc1d23 is a ...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-30840 | biostudies-arrayexpress
UnknownOne-year safety and efficacy study of arformoterol tartrate in patients with moderate to severe COPD.
Not available
S-EPMC4251615 | biostudies-literature
GenomicsA comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing
As whole genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Using tumor-normal sample pairs from two different types of cancer, chronic lymphocytic leukemia and medulloblastoma, we conducted a ...
EGAS00001001539 | EGA
TranscriptomicsTranscriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS) - Illumina arrays
These microarrays were performed for use in a genome-wide scan for LPS-regulated genes in human monocyte-derived macrophages, in order to construct a list of LPS-regulated genes for detailed interrogation on custom microarrays (see GSE19482 for custom array analysis). Human monocyte-derived macropha...
ORGANISM(S): Homo sapiens 
2012-03-28 | E-GEOD-19765 | biostudies-arrayexpress
UnknownReanalysis of RNA sequencing data ends diagnostic odyssey and expands the phenotypic spectrum of congenital titinopathy.
Not available
S-EPMC11934095 | biostudies-literature
ProteomicsQuantitative differences in rumen epithelium proteins in lambs fed wheat, perennial wheat or perennial wheat plus lucerne.
The rumen is a major the site of digestion and absorption of energy predominantly in the form of short chain fatty acids as well as amino acids and simple carbohydrates. The value of crops such as perennial wheat (PW) for grain and grazing compared to conventional wheat (W), or the addition of lucer...
ORGANISM(S): Ovis aries 
2023-10-24 | PXD044135 | Pride
Epithelium Nutrient Transport Tmt-ms Rumen Proteome Membrane 
TranscriptomicsTranscriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS)
Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agon...
ORGANISM(S): Homo sapiens 
2012-03-28 | E-GEOD-19482 | biostudies-arrayexpress
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