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ProteomicsCellular internalization pathways of environmentally exposed microplastic particles
Microplastic particles that occur in the environment are coated with different biomolecules forming an eco-corona on the particles' surface, which could consequently lead to a specific interaction of the constituents of the eco-corona with membrane receptors. To date, it is not fully understood how ...
ORGANISM(S): biofilm metagenome 
2025-03-07 | PXD050078 | Pride
Eco-corona Microplastic 
UnknownAssessing Privacy Vulnerabilities in Genetic Data Sets: Scoping Review.
Not available
S-EPMC11165293 | biostudies-literature
UnknownInflammation leads through PGE/EP3 signaling to HDAC5/MEF2-dependent transcription in cardiac myocytes.
Not available
S-EPMC6034133 | biostudies-literature
Proteomics,MultiomicsA deep proteome and transcriptome abundance atlas of 29 healthy human tissues
We generated a systematic, quantitative and deep proteome and transcriptome abundance atlas from 29 paired healthy human to serve as a molecular baseline to study human biology.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-02 | MSV000083508 | MassIVE
ProteomicsPolymer type specific microplastic effects on Dreissena bugensis’ proteome, antioxidant activity and behavior
The freshwater mussel Dreissena bugensis was exposed for nine days to different microplastic particles, in detail, to three petroleum-based polymers (polyamide (PA), polyethylene terephthalate (PET), polystyrene (PS)), to one bio-based polymer (polylactic acid (PLA)) and to ground mussel shells (MS)...
ORGANISM(S): Dreissena rostriformis bugensis 
2022-11-11 | PXD030056 | Pride
Proteomics Filter feeders Microplastics Real-time valvometry Antioxidant activity 
ProteomicsAPEX2 mediated proximity labeling to investigate the proximal proteome of mitochondria tethered ULK1 in wild type and fip200 knock down cells
The object of this project is to investigate the proximal proteome of ULK1 during mitophagy and the effects of a FIP200 knock down using the APEX2-mediated proximity labeling system. APEX2-ULK1 or APEX2 was fused to 2xFKBP-myc and stably expressed in a cell line stably expressing a truncated FIS1-FR...
ORGANISM(S): Homo sapiens (Human) 
2024-10-12 | PXD047277 | Pride
Fip200 Mitophagy Autophagy Frb-rapalog-fkbp interaction Ulk1 Apex2 Er 
UnknownELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy.
Not available
S-EPMC3738821 | biostudies-literature
UnknownAngiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.
Not available
S-EPMC3366398 | biostudies-literature
MetabolomicsComprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...
2015-11-19 | MTBLS143 | MetaboLights
UnknownMutations in FBXL4, encoding a mitochondrial protein, cause early-onset mitochondrial encephalomyopathy.
Not available
S-EPMC3769923 | biostudies-literature
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